| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 24 | 24 | 7 | 5 | 3.28 | .288 | 1.17 | 6.7 | 3.9 | 8.8 | 112.1 | 83 | 41 | 41 | 10 | 48 | 110 | 0 | 0 | 0 | 0 | 2 | 5 | 5 | 3.62 |
| SP | Perez, O.Perez, Odalis # >> | 25 | 2002 | L | 81 | 24 | 24 | 8 | 10 | 4.88 | .294 | 1.22 | 8.9 | 2.2 | 6.6 | 158.2 | 156 | 88 | 86 | 27 | 38 | 115 | 4 | 0 | 0 | 1 | 10 | 4 | 1 | 4.56 |
| SP | Willis, D.Willis, Dontrelle † >> | 23 | 2005 | L | 48 | 23 | 23 | 10 | 9 | 4.86 | .314 | 1.33 | 9.4 | 2.6 | 7.0 | 144.1 | 150 | 81 | 78 | 24 | 42 | 112 | 4 | 0 | 0 | 2 | 9 | 6 | 1 | 4.61 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 22 | 22 | 6 | 5 | 5.29 | .329 | 1.41 | 9.1 | 3.7 | 6.2 | 127.2 | 128 | 76 | 75 | 21 | 52 | 87 | 0 | 0 | 0 | 0 | 11 | 8 | 6 | 5.20 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 69 | 0 | 3 | 4 | 4.81 | .304 | 1.28 | 9.4 | 2.2 | 9.8 | 91.2 | 95 | 50 | 49 | 11 | 22 | 99 | 0 | 6 | 6 | 0 | 0 | 3 | 1 | 3.22 |
| RP | Gordon, T.Gordon, Tom # >> | 37 | 2004 | R | 81 | 60 | 0 | 3 | 6 | 4.97 | .287 | 1.19 | 8.1 | 2.7 | 8.1 | 79.2 | 71 | 44 | 44 | 14 | 24 | 71 | 0 | 7 | 3 | 0 | 0 | 1 | 1 | 4.46 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 59 | 54 | 0 | 5 | 4 | 3.70 | .251 | 1.01 | 6.0 | 3.2 | 9.8 | 65.2 | 43 | 28 | 27 | 11 | 23 | 71 | 0 | 3 | 3 | 0 | 0 | 0 | 2 | 4.08 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 45 | 37 | 0 | 1 | 1 | 2.32 | .251 | 1.01 | 6.2 | 3.0 | 8.1 | 42.2 | 29 | 13 | 11 | 3 | 14 | 38 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 3.12 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 34 | 31 | 0 | 4 | 4 | 9.00 | .400 | 1.94 | 10.3 | 7.1 | 7.9 | 34.0 | 39 | 34 | 34 | 10 | 27 | 30 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 7.62 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 36 | 24 | 0 | 1 | 3 | 5.59 | .352 | 1.63 | 9.0 | 5.9 | 6.9 | 38.2 | 38 | 24 | 24 | 5 | 25 | 29 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 5.16 |