| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 30 | 30 | 15 | 8 | 4.27 | .300 | 1.27 | 8.6 | 2.8 | 8.3 | 204.1 | 195 | 101 | 97 | 28 | 64 | 189 | 3 | 0 | 0 | 0 | 19 | 4 | 5 | 3.93 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 82 | 29 | 29 | 14 | 6 | 4.24 | .293 | 1.20 | 8.8 | 2.0 | 5.9 | 220.2 | 216 | 107 | 104 | 33 | 49 | 143 | 7 | 0 | 0 | 1 | 16 | 10 | 2 | 4.45 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 51 | 29 | 29 | 10 | 9 | 6.29 | .351 | 1.61 | 9.9 | 4.6 | 6.8 | 163.0 | 179 | 116 | 114 | 34 | 83 | 123 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 5.79 |
| SP | Willis, D.Willis, Dontrelle † # >> | 23 | 2005 | L | 50 | 28 | 28 | 14 | 9 | 4.02 | .302 | 1.26 | 8.9 | 2.4 | 6.3 | 210.2 | 208 | 99 | 94 | 22 | 57 | 147 | 6 | 0 | 0 | 0 | 13 | 8 | 3 | 3.89 |
| RP | Rhodes, A.Rhodes, Arthur # >> | 32 | 2001 | L | 83 | 74 | 0 | 5 | 10 | 5.34 | .299 | 1.25 | 9.1 | 2.3 | 9.9 | 87.2 | 88 | 52 | 52 | 17 | 22 | 96 | 0 | 11 | 4 | 0 | 0 | 2 | 4 | 4.16 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 47 | 0 | 0 | 1 | 6.40 | .353 | 1.60 | 10.6 | 3.8 | 9.5 | 52.0 | 61 | 37 | 37 | 10 | 22 | 55 | 0 | 7 | 5 | 0 | 0 | 2 | 0 | 4.77 |
| RP | Williamson, S.Williamson, Scott >> | 26 | 2002 | R | 52 | 37 | 0 | 6 | 1 | 4.17 | .306 | 1.32 | 6.8 | 5.2 | 9.0 | 45.1 | 34 | 21 | 21 | 9 | 26 | 45 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 5.33 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 44 | 34 | 0 | 3 | 1 | 5.12 | .356 | 1.63 | 11.4 | 3.6 | 7.8 | 38.2 | 48 | 23 | 22 | 5 | 15 | 33 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.24 |