| SP | Santana, J.Santana, Johan $ >> | 25 | 2004 | L | 100 | 4 | 4 | 2 | 0 | 4.39 | .298 | 1.28 | 6.9 | 4.8 | 8.7 | 26.2 | 20 | 13 | 13 | 4 | 14 | 25 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 4.69 |
| SP | Weaver, J.Weaver, Jered $$ >> | 24 | 2006 | R | 83 | 4 | 4 | 1 | 3 | 7.08 | .330 | 1.43 | 9.5 | 3.6 | 9.0 | 20.1 | 21 | 17 | 16 | 3 | 8 | 20 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 4.30 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 81 | 4 | 4 | 0 | 3 | 6.75 | .390 | 1.92 | 15.0 | 2.6 | 8.6 | 21.1 | 35 | 18 | 16 | 5 | 6 | 20 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 5.05 |
| SP | Garcia, F.Garcia, Freddy >> | 25 | 2001 | R | 62 | 4 | 4 | 1 | 1 | 7.33 | .358 | 1.63 | 11.3 | 3.5 | 7.8 | 23.1 | 29 | 19 | 19 | 4 | 9 | 20 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.83 |
| CL | Papelbon, J.Papelbon, Jonathan $$ >> | 26 | 2006 | R | 94 | 10 | 0 | 4 | 1 | 2.38 | .190 | 0.71 | 4.1 | 2.5 | 9.0 | 11.1 | 5 | 3 | 3 | 2 | 3 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.18 |
| SU | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 86 | 6 | 0 | 0 | 0 | 3.60 | .375 | 1.80 | 10.8 | 5.4 | 3.6 | 5.0 | 6 | 2 | 2 | 1 | 3 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 6.60 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 8 | 0 | 1 | 0 | 2.08 | .395 | 1.85 | 10.1 | 7.9 | 11.3 | 8.2 | 9 | 2 | 2 | 0 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.50 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 10 | 0 | 0 | 0 | 2.38 | .227 | 0.88 | 5.7 | 2.5 | 9.8 | 11.1 | 7 | 3 | 3 | 0 | 3 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.64 |
| RP | Valverde, J.Valverde, Jose $ >> | 24 | 2003 | R | 79 | 10 | 0 | 0 | 0 | 1.54 | .300 | 1.20 | 3.3 | 8.2 | 12.3 | 11.2 | 4 | 2 | 2 | 0 | 10 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.27 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 68 | 6 | 0 | 0 | 0 | 4.91 | .241 | 0.95 | 7.7 | 1.3 | 10.3 | 7.1 | 6 | 4 | 4 | 1 | 1 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 7 | 0 | 0 | 0 | 16.62 | .519 | 3.23 | 27.0 | 4.5 | 13.5 | 4.1 | 12 | 8 | 8 | 5 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 17.75 |