| SP | Johnson, R.Johnson, Randy † # >> | 38 | 2001 | L | 97 | 30 | 30 | 14 | 7 | 3.89 | .284 | 1.17 | 7.7 | 2.8 | 9.9 | 219.2 | 187 | 96 | 95 | 36 | 69 | 242 | 2 | 0 | 0 | 0 | 17 | 5 | 4 | 3.94 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 29 | 29 | 10 | 11 | 4.38 | .300 | 1.26 | 9.1 | 2.3 | 6.4 | 207.1 | 209 | 115 | 101 | 27 | 53 | 147 | 6 | 0 | 0 | 2 | 13 | 5 | 4 | 4.12 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 29 | 17 | 4 | 5 | 4.59 | .346 | 1.56 | 9.7 | 4.4 | 6.4 | 127.1 | 137 | 75 | 65 | 16 | 62 | 91 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.74 |
| SP | Park, C.Park, Chan Ho # >> | 28 | 2001 | R | 59 | 28 | 28 | 15 | 4 | 5.03 | .328 | 1.43 | 9.2 | 3.7 | 6.3 | 171.2 | 174 | 101 | 96 | 20 | 71 | 119 | 2 | 0 | 0 | 1 | 13 | 6 | 5 | 4.48 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 82 | 0 | 6 | 7 | 3.42 | .254 | 0.99 | 6.2 | 2.7 | 6.7 | 92.0 | 63 | 38 | 35 | 15 | 28 | 68 | 0 | 7 | 4 | 0 | 0 | 3 | 2 | 4.65 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 62 | 0 | 6 | 5 | 4.00 | .341 | 1.54 | 8.0 | 5.9 | 9.3 | 63.0 | 56 | 31 | 28 | 5 | 41 | 65 | 0 | 8 | 2 | 0 | 0 | 1 | 1 | 3.97 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 85 | 37 | 0 | 3 | 1 | 5.06 | .356 | 1.66 | 10.1 | 4.8 | 8.7 | 32.0 | 36 | 18 | 18 | 9 | 17 | 31 | 0 | 5 | 2 | 0 | 0 | 0 | 2 | 6.31 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 29 | 12 | 5 | 9 | 7.61 | .375 | 1.77 | 12.5 | 3.4 | 6.9 | 110.0 | 153 | 96 | 93 | 25 | 42 | 84 | 0 | 0 | 1 | 0 | 2 | 3 | 5 | 5.65 |