| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 11 | 6 | 3.57 | .310 | 1.33 | 7.9 | 4.1 | 7.3 | 141.0 | 123 | 61 | 56 | 17 | 64 | 115 | 0 | 0 | 0 | 0 | 15 | 3 | 1 | 4.36 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 19 | 19 | 8 | 10 | 4.09 | .288 | 1.20 | 6.5 | 4.3 | 7.7 | 114.1 | 82 | 58 | 52 | 10 | 55 | 98 | 0 | 0 | 0 | 0 | 11 | 2 | 1 | 3.92 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 19 | 19 | 5 | 9 | 4.74 | .308 | 1.32 | 9.0 | 2.9 | 6.4 | 106.1 | 106 | 76 | 56 | 23 | 34 | 75 | 0 | 0 | 0 | 0 | 9 | 2 | 4 | 5.42 |
| SP | Valenzuela, F.Valenzuela, Fernando # >> | 21 | 1981 | L | 60 | 18 | 17 | 8 | 7 | 4.20 | .334 | 1.49 | 8.7 | 4.8 | 7.5 | 115.2 | 111 | 60 | 54 | 17 | 61 | 96 | 3 | 0 | 0 | 1 | 10 | 2 | 1 | 4.90 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 54 | 0 | 0 | 1 | 3.88 | .295 | 1.21 | 8.4 | 2.6 | 10.3 | 48.2 | 45 | 24 | 21 | 7 | 14 | 55 | 0 | 8 | 3 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 71 | 38 | 0 | 3 | 3 | 5.97 | .307 | 1.29 | 7.0 | 4.9 | 11.9 | 31.2 | 24 | 22 | 21 | 6 | 17 | 41 | 0 | 7 | 4 | 0 | 0 | 1 | 1 | 4.61 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 12 | 0 | 0 | 0 | 1.17 | .207 | 0.78 | 4.2 | 3.0 | 9.0 | 15.1 | 7 | 2 | 2 | 1 | 5 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.87 |
| SP | Koosman, J.Koosman, Jerry >> | 34 | 1976 | L | 24 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |