| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 26 | 26 | 11 | 8 | 4.43 | .305 | 1.30 | 8.4 | 3.3 | 10.0 | 142.1 | 133 | 72 | 70 | 26 | 52 | 157 | 2 | 0 | 0 | 1 | 15 | 2 | 2 | 4.31 |
| SP | Flaherty, J.Flaherty, Jack # >> | 23 | 2019 | R | 82 | 25 | 25 | 7 | 13 | 3.96 | .306 | 1.29 | 9.1 | 2.6 | 9.5 | 147.2 | 149 | 70 | 65 | 23 | 42 | 155 | 2 | 0 | 0 | 0 | 16 | 4 | 2 | 3.86 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 25 | 25 | 5 | 12 | 4.58 | .325 | 1.42 | 8.1 | 4.7 | 8.2 | 137.2 | 124 | 76 | 70 | 14 | 72 | 125 | 0 | 0 | 0 | 0 | 10 | 3 | 2 | 4.15 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 58 | 24 | 24 | 8 | 9 | 5.16 | .340 | 1.50 | 10.1 | 3.4 | 7.0 | 139.2 | 156 | 87 | 80 | 20 | 53 | 108 | 0 | 0 | 0 | 0 | 9 | 7 | 4 | 4.61 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 50 | 27 | 24 | 6 | 8 | 4.24 | .329 | 1.47 | 7.9 | 5.4 | 4.6 | 152.2 | 134 | 85 | 72 | 20 | 91 | 77 | 2 | 0 | 0 | 1 | 11 | 0 | 3 | 5.49 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 81 | 0 | 5 | 3 | 3.48 | .269 | 1.09 | 6.2 | 3.6 | 8.8 | 111.1 | 77 | 45 | 43 | 17 | 44 | 109 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 4.27 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 73 | 0 | 6 | 2 | 4.07 | .311 | 1.33 | 9.8 | 2.3 | 8.9 | 90.2 | 98 | 42 | 41 | 11 | 23 | 89 | 0 | 9 | 3 | 0 | 0 | 2 | 0 | 3.44 |
| RP | Brewer, J.Brewer, Jim # >> | 35 | 1972 | L | 72 | 84 | 0 | 2 | 3 | 6.54 | .331 | 1.45 | 9.0 | 4.1 | 5.9 | 63.1 | 63 | 47 | 46 | 11 | 29 | 41 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.44 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 54 | 49 | 0 | 5 | 6 | 3.31 | .306 | 1.25 | 8.0 | 3.3 | 9.7 | 54.1 | 48 | 22 | 20 | 8 | 20 | 58 | 0 | 2 | 1 | 0 | 0 | 4 | 6 | 4.11 |