| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 22 | 22 | 7 | 13 | 4.97 | .300 | 1.26 | 8.9 | 2.4 | 6.5 | 152.0 | 151 | 90 | 84 | 26 | 41 | 109 | 4 | 0 | 0 | 0 | 8 | 3 | 2 | 4.66 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 22 | 22 | 5 | 8 | 3.54 | .307 | 1.31 | 7.3 | 4.6 | 8.8 | 134.2 | 109 | 55 | 53 | 17 | 68 | 131 | 0 | 0 | 0 | 0 | 13 | 2 | 4 | 4.26 |
| SP | Valenzuela, F.Valenzuela, Fernando # >> | 21 | 1981 | L | 61 | 17 | 16 | 8 | 4 | 3.48 | .290 | 1.22 | 7.1 | 3.9 | 6.9 | 121.2 | 95 | 50 | 47 | 17 | 53 | 93 | 7 | 0 | 0 | 1 | 9 | 1 | 1 | 4.63 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 47 | 18 | 18 | 7 | 6 | 4.80 | .330 | 1.41 | 8.9 | 3.8 | 6.3 | 105.0 | 104 | 58 | 56 | 17 | 44 | 73 | 0 | 0 | 0 | 0 | 10 | 7 | 2 | 5.17 |
| RP | Green, C.Green, Chad # >> | 26 | 2017 | R | 95 | 57 | 0 | 4 | 1 | 3.21 | .267 | 1.08 | 6.3 | 3.4 | 11.3 | 95.1 | 67 | 35 | 34 | 8 | 36 | 119 | 0 | 6 | 4 | 0 | 0 | 1 | 4 | 2.76 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 27 | 0 | 5 | 0 | 2.67 | .316 | 1.35 | 6.6 | 5.7 | 8.1 | 30.1 | 22 | 9 | 9 | 1 | 19 | 27 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.63 |
| RP | Nathan, J.Nathan, Joe # >> | 32 | 2006 | R | 85 | 25 | 0 | 2 | 3 | 4.94 | .274 | 1.13 | 6.7 | 3.7 | 11.0 | 27.1 | 20 | 15 | 15 | 6 | 11 | 33 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.67 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 5 | 1 | 0 | 2 | 8.64 | .457 | 2.52 | 14.6 | 9.0 | 11.3 | 8.1 | 13 | 8 | 8 | 4 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 10.00 |