| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 26 | 26 | 12 | 11 | 3.46 | .278 | 1.14 | 7.6 | 2.7 | 7.9 | 166.1 | 141 | 66 | 64 | 18 | 49 | 145 | 6 | 0 | 0 | 1 | 16 | 2 | 5 | 3.58 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 25 | 25 | 12 | 3 | 3.52 | .285 | 1.18 | 7.9 | 2.7 | 9.9 | 156.0 | 137 | 62 | 61 | 16 | 47 | 172 | 2 | 0 | 0 | 0 | 17 | 3 | 2 | 3.09 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 59 | 0 | 6 | 3 | 1.50 | .205 | 0.76 | 4.8 | 2.0 | 9.5 | 66.0 | 35 | 11 | 11 | 2 | 15 | 70 | 0 | 29 | 1 | 0 | 0 | 1 | 0 | 2.00 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 90 | 68 | 0 | 2 | 2 | 2.42 | .229 | 0.89 | 6.2 | 1.9 | 10.9 | 70.2 | 48 | 19 | 19 | 9 | 15 | 85 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.89 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 58 | 0 | 6 | 3 | 5.37 | .342 | 1.54 | 7.7 | 6.3 | 11.7 | 60.1 | 51 | 36 | 36 | 9 | 42 | 78 | 0 | 1 | 2 | 0 | 0 | 1 | 7 | 4.50 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 58 | 0 | 2 | 1 | 3.84 | .302 | 1.24 | 6.5 | 4.8 | 8.7 | 58.2 | 42 | 26 | 25 | 4 | 31 | 56 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.72 |