| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 26 | 26 | 10 | 11 | 3.55 | .304 | 1.28 | 8.3 | 3.3 | 9.1 | 177.1 | 163 | 74 | 70 | 21 | 64 | 178 | 3 | 0 | 0 | 1 | 16 | 5 | 5 | 3.70 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 25 | 25 | 6 | 15 | 6.46 | .367 | 1.71 | 11.2 | 4.3 | 9.0 | 129.2 | 161 | 94 | 93 | 21 | 61 | 129 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 4.63 |
| SP | Harvey, M.Harvey, Matt # >> | 24 | 2013 | R | 77 | 25 | 25 | 12 | 9 | 3.36 | .287 | 1.20 | 9.2 | 1.7 | 8.5 | 158.0 | 161 | 67 | 59 | 22 | 29 | 149 | 0 | 0 | 0 | 0 | 18 | 1 | 1 | 3.49 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 26 | 24 | 10 | 12 | 4.31 | .325 | 1.43 | 9.8 | 3.1 | 6.6 | 177.1 | 193 | 92 | 85 | 23 | 60 | 129 | 5 | 0 | 0 | 2 | 11 | 3 | 6 | 4.30 |
| CL | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 89 | 45 | 0 | 2 | 4 | 1.80 | .257 | 1.04 | 5.8 | 3.6 | 9.0 | 50.0 | 32 | 10 | 10 | 3 | 20 | 50 | 0 | 23 | 2 | 0 | 0 | 0 | 0 | 2.98 |
| SU | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 34 | 0 | 0 | 2 | 3.22 | .302 | 1.25 | 7.0 | 4.5 | 7.6 | 44.2 | 34 | 17 | 16 | 6 | 22 | 37 | 0 | 1 | 4 | 0 | 0 | 2 | 5 | 4.73 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 30 | 0 | 1 | 0 | 2.97 | .331 | 1.48 | 6.3 | 7.2 | 8.7 | 30.1 | 21 | 13 | 10 | 3 | 24 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.77 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 48 | 0 | 2 | 2 | 3.30 | .304 | 1.29 | 7.1 | 4.6 | 10.4 | 57.1 | 45 | 25 | 21 | 10 | 29 | 66 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.54 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 22 | 0 | 1 | 1 | 2.35 | .296 | 1.26 | 8.2 | 3.1 | 10.2 | 23.0 | 21 | 7 | 6 | 0 | 8 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 1.78 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 24 | 0 | 0 | 0 | 3.71 | .266 | 1.09 | 6.6 | 3.5 | 12.8 | 26.2 | 19 | 11 | 11 | 7 | 10 | 37 | 0 | 6 | 1 | 0 | 0 | 0 | 4 | 4.81 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 19 | 6 | 2 | 5 | 6.24 | .322 | 1.39 | 9.5 | 3.1 | 8.0 | 79.1 | 83 | 56 | 55 | 13 | 27 | 70 | 0 | 0 | 0 | 0 | 2 | 3 | 3 | 4.51 |