| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 34 | 34 | 13 | 10 | 4.24 | .319 | 1.38 | 9.5 | 2.9 | 8.2 | 227.1 | 240 | 118 | 107 | 24 | 74 | 208 | 2 | 0 | 0 | 1 | 21 | 6 | 4 | 3.60 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 10 | 10 | 4 | 4 | 6.20 | .366 | 1.71 | 10.4 | 5.3 | 5.9 | 53.2 | 61 | 40 | 37 | 7 | 31 | 35 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 5.21 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 31 | 20 | 20 | 6 | 12 | 5.16 | .332 | 1.47 | 8.4 | 4.8 | 6.1 | 129.0 | 120 | 82 | 74 | 13 | 69 | 87 | 3 | 0 | 0 | 0 | 9 | 3 | 2 | 4.64 |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 44 | 14 | 11 | 3 | 8 | 6.22 | .367 | 1.74 | 9.8 | 6.0 | 5.1 | 72.1 | 78 | 53 | 50 | 10 | 48 | 41 | 0 | 0 | 0 | 0 | 4 | 0 | 6 | 5.67 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 31 | 29 | 12 | 13 | 5.68 | .337 | 1.51 | 10.2 | 3.4 | 6.7 | 179.0 | 203 | 117 | 113 | 28 | 67 | 134 | 1 | 0 | 0 | 0 | 14 | 3 | 1 | 4.71 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 80 | 0 | 3 | 1 | 5.03 | .310 | 1.31 | 8.9 | 3.0 | 9.9 | 87.2 | 86 | 50 | 49 | 15 | 29 | 96 | 0 | 2 | 4 | 0 | 0 | 3 | 4 | 4.14 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 64 | 0 | 4 | 1 | 4.20 | .305 | 1.29 | 8.9 | 2.8 | 4.6 | 70.2 | 69 | 36 | 33 | 10 | 22 | 36 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.86 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 36 | 99 | 0 | 0 | 0 | 4.60 | .286 | 1.14 | 6.4 | 3.8 | 8.1 | 88.0 | 63 | 46 | 45 | 13 | 37 | 79 | 0 | 2 | 0 | 0 | 0 | 6 | 0 | 4.59 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 32 | 5 | 5 | 8 | 6.26 | .342 | 1.54 | 9.1 | 4.8 | 5.6 | 83.1 | 84 | 67 | 58 | 13 | 44 | 52 | 0 | 1 | 0 | 0 | 2 | 2 | 7 | 5.45 |