| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 16 | 16 | 4 | 7 | 4.51 | .292 | 1.22 | 8.3 | 2.8 | 9.6 | 101.2 | 93 | 52 | 51 | 16 | 31 | 108 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 3.90 |
| SP | Cole, G.Cole, Gerrit $$ >> | 28 | 2019 | R | 92 | 16 | 16 | 8 | 4 | 4.79 | .317 | 1.38 | 8.5 | 4.0 | 10.2 | 99.2 | 94 | 54 | 53 | 14 | 44 | 112 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 3.94 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 16 | 16 | 5 | 4 | 3.83 | .300 | 1.28 | 9.3 | 2.2 | 9.1 | 110.1 | 114 | 47 | 47 | 21 | 27 | 111 | 2 | 0 | 0 | 0 | 9 | 1 | 0 | 4.23 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 16 | 16 | 5 | 6 | 5.34 | .307 | 1.27 | 9.6 | 2.0 | 4.8 | 92.2 | 98 | 58 | 55 | 17 | 20 | 49 | 2 | 0 | 0 | 0 | 7 | 5 | 1 | 5.15 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 34 | 0 | 3 | 7 | 3.75 | .270 | 1.03 | 6.3 | 3.0 | 9.5 | 36.0 | 25 | 16 | 15 | 3 | 12 | 38 | 0 | 17 | 0 | 0 | 0 | 3 | 1 | 3.22 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 31 | 0 | 1 | 1 | 6.35 | .375 | 1.76 | 12.5 | 3.5 | 9.3 | 28.1 | 39 | 20 | 20 | 7 | 11 | 29 | 0 | 1 | 5 | 0 | 0 | 1 | 0 | 5.46 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 42 | 0 | 4 | 1 | 2.63 | .234 | 0.90 | 5.6 | 2.5 | 8.1 | 51.1 | 32 | 15 | 15 | 5 | 14 | 46 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.35 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 22 | 0 | 1 | 1 | 5.66 | .354 | 1.60 | 9.5 | 5.4 | 13.1 | 20.2 | 21 | 13 | 13 | 6 | 12 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.95 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 21 | 0 | 2 | 0 | 2.38 | .261 | 1.06 | 6.1 | 3.7 | 7.0 | 22.2 | 15 | 6 | 6 | 4 | 9 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.05 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 10 | 0 | 2 | 1 | 5.94 | .323 | 1.40 | 9.5 | 3.3 | 5.3 | 36.1 | 38 | 25 | 24 | 5 | 13 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.81 |