| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 34 | 34 | 11 | 10 | 3.63 | .278 | 1.13 | 7.3 | 2.9 | 8.1 | 248.0 | 201 | 102 | 100 | 41 | 80 | 222 | 1 | 0 | 0 | 0 | 24 | 5 | 3 | 4.39 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 33 | 33 | 7 | 21 | 5.72 | .339 | 1.50 | 10.2 | 3.4 | 4.6 | 210.2 | 238 | 143 | 134 | 29 | 79 | 108 | 5 | 0 | 0 | 2 | 12 | 7 | 1 | 5.00 |
| SP | Camnitz, H.Camnitz, Howie # >> | 28 | 1909 | R | 58 | 31 | 31 | 14 | 12 | 4.30 | .309 | 1.33 | 9.1 | 2.8 | 3.6 | 220.0 | 223 | 119 | 105 | 24 | 69 | 87 | 6 | 0 | 0 | 2 | 17 | 3 | 3 | 4.61 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 83 | 0 | 4 | 6 | 5.32 | .322 | 1.41 | 10.3 | 2.5 | 9.7 | 111.2 | 127 | 67 | 66 | 15 | 31 | 120 | 0 | 7 | 5 | 0 | 0 | 1 | 3 | 3.46 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 86 | 0 | 6 | 4 | 5.65 | .353 | 1.59 | 8.6 | 5.8 | 8.3 | 100.1 | 96 | 67 | 63 | 11 | 64 | 92 | 0 | 5 | 3 | 0 | 0 | 4 | 2 | 4.63 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 74 | 0 | 3 | 7 | 5.04 | .332 | 1.46 | 9.1 | 4.1 | 8.4 | 85.2 | 86 | 51 | 48 | 12 | 39 | 79 | 0 | 4 | 5 | 0 | 0 | 3 | 2 | 4.46 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 64 | 0 | 4 | 2 | 4.99 | .311 | 1.34 | 8.4 | 3.6 | 8.1 | 74.0 | 69 | 41 | 41 | 11 | 30 | 67 | 0 | 3 | 3 | 0 | 0 | 1 | 9 | 4.38 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 36 | 2 | 8 | 4 | 6.69 | .362 | 1.70 | 12.3 | 3.0 | 7.6 | 70.0 | 96 | 56 | 52 | 10 | 23 | 59 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 4.16 |