| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 11 | 11 | 4 | 5 | 3.65 | .275 | 1.11 | 7.1 | 2.9 | 8.7 | 86.1 | 68 | 37 | 35 | 9 | 28 | 83 | 5 | 0 | 0 | 0 | 6 | 2 | 1 | 3.48 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 9 | 9 | 7 | 1 | 3.30 | .291 | 1.22 | 7.1 | 3.9 | 5.1 | 60.0 | 47 | 22 | 22 | 5 | 26 | 34 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 4.30 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 10 | 10 | 6 | 4 | 4.07 | .287 | 1.21 | 8.5 | 2.3 | 3.9 | 73.0 | 69 | 33 | 33 | 5 | 19 | 32 | 4 | 0 | 0 | 2 | 4 | 0 | 3 | 3.79 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 30 | 0 | 1 | 1 | 1.84 | .307 | 1.30 | 7.8 | 4.0 | 10.6 | 29.1 | 25 | 6 | 6 | 1 | 13 | 34 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.55 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 19 | 0 | 0 | 3 | 3.86 | .315 | 1.33 | 10.7 | 1.3 | 4.7 | 21.0 | 25 | 9 | 9 | 2 | 3 | 11 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.76 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 14 | 0 | 1 | 1 | 2.92 | .288 | 1.14 | 7.5 | 3.0 | 2.3 | 12.1 | 10 | 4 | 4 | 1 | 4 | 3 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.83 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 5 | 0 | 0 | 0 | 9.00 | .471 | 2.67 | 15.0 | 9.0 | 15.0 | 3.0 | 5 | 3 | 3 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 7 | 0 | 0 | 0 | 1.86 | .171 | 0.62 | 3.0 | 3.0 | 9.0 | 9.2 | 3 | 2 | 2 | 2 | 3 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.89 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 3 | 2 | 1 | 1 | 4.15 | .333 | 1.50 | 9.5 | 4.2 | 5.3 | 17.1 | 18 | 10 | 8 | 2 | 8 | 10 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.76 |