| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 6 | 6 | 3 | 0 | 2.70 | .273 | 1.13 | 7.9 | 2.3 | 9.5 | 40.0 | 35 | 12 | 12 | 4 | 10 | 42 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 2.95 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 6 | 6 | 1 | 2 | 8.47 | .382 | 1.85 | 11.1 | 5.6 | 5.8 | 34.0 | 42 | 33 | 32 | 8 | 21 | 22 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 6.62 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 6 | 6 | 1 | 2 | 4.62 | .320 | 1.33 | 8.8 | 3.2 | 4.4 | 39.0 | 38 | 20 | 20 | 5 | 14 | 19 | 1 | 0 | 0 | 0 | 4 | 3 | 0 | 5.00 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 16 | 0 | 0 | 2 | 5.70 | .330 | 1.48 | 9.0 | 4.7 | 9.4 | 23.2 | 23 | 15 | 15 | 3 | 12 | 24 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 13 | 0 | 0 | 3 | 4.96 | .347 | 1.59 | 11.3 | 3.4 | 7.3 | 16.1 | 20 | 10 | 9 | 2 | 6 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.13 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 6 | 0 | 0 | 1 | 13.50 | .471 | 2.67 | 15.0 | 9.0 | 3.0 | 6.0 | 10 | 9 | 9 | 3 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.83 |