| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 36 | 36 | 13 | 15 | 4.37 | .300 | 1.25 | 8.7 | 2.5 | 10.4 | 202.0 | 196 | 102 | 98 | 28 | 56 | 234 | 2 | 0 | 0 | 2 | 18 | 8 | 0 | 3.44 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 34 | 33 | 10 | 11 | 5.60 | .347 | 1.56 | 10.5 | 3.6 | 6.7 | 181.2 | 211 | 124 | 113 | 24 | 73 | 134 | 2 | 0 | 0 | 0 | 12 | 5 | 8 | 4.54 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 37 | 31 | 15 | 7 | 4.92 | .331 | 1.45 | 9.4 | 3.7 | 5.1 | 188.1 | 196 | 111 | 103 | 19 | 77 | 107 | 2 | 0 | 0 | 0 | 17 | 6 | 6 | 4.50 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 94 | 0 | 12 | 7 | 3.33 | .285 | 1.19 | 7.0 | 3.7 | 10.8 | 108.0 | 84 | 44 | 40 | 12 | 44 | 130 | 0 | 35 | 6 | 0 | 0 | 1 | 6 | 3.29 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 69 | 0 | 6 | 0 | 3.90 | .301 | 1.28 | 9.1 | 2.4 | 8.7 | 92.1 | 93 | 42 | 40 | 13 | 25 | 89 | 0 | 2 | 1 | 0 | 0 | 1 | 4 | 3.75 |