| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 25 | 25 | 9 | 13 | 4.68 | .315 | 1.36 | 9.6 | 2.6 | 8.4 | 171.0 | 183 | 91 | 89 | 30 | 50 | 159 | 1 | 0 | 0 | 0 | 12 | 3 | 2 | 4.35 |
| SP | Maddux, G.Maddux, Greg † $$ >> | 29 | 1995 | R | 89 | 24 | 24 | 14 | 6 | 2.98 | .240 | 0.93 | 6.8 | 1.6 | 5.9 | 178.1 | 135 | 60 | 59 | 18 | 31 | 116 | 6 | 0 | 0 | 1 | 16 | 3 | 2 | 3.58 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 24 | 24 | 10 | 12 | 4.44 | .277 | 1.14 | 8.2 | 2.1 | 6.0 | 164.1 | 149 | 86 | 81 | 24 | 38 | 110 | 4 | 0 | 0 | 0 | 13 | 2 | 3 | 4.29 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 24 | 24 | 10 | 9 | 5.99 | .336 | 1.50 | 10.8 | 2.8 | 7.2 | 139.2 | 167 | 96 | 93 | 28 | 43 | 111 | 2 | 0 | 0 | 1 | 8 | 2 | 1 | 4.99 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 22 | 22 | 8 | 8 | 5.83 | .338 | 1.50 | 10.8 | 2.8 | 5.7 | 146.2 | 175 | 100 | 95 | 22 | 45 | 92 | 5 | 0 | 0 | 1 | 6 | 5 | 0 | 4.73 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 65 | 0 | 2 | 4 | 2.90 | .246 | 0.96 | 7.3 | 1.3 | 8.7 | 90.0 | 73 | 30 | 29 | 13 | 13 | 87 | 0 | 10 | 1 | 0 | 0 | 2 | 1 | 3.44 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 59 | 0 | 5 | 3 | 3.68 | .303 | 1.26 | 7.6 | 3.9 | 8.6 | 63.2 | 53 | 26 | 26 | 4 | 27 | 60 | 0 | 9 | 3 | 0 | 0 | 3 | 0 | 3.35 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 43 | 0 | 2 | 1 | 3.64 | .297 | 1.27 | 7.7 | 3.8 | 8.0 | 54.1 | 46 | 24 | 22 | 11 | 23 | 48 | 0 | 6 | 0 | 0 | 0 | 0 | 2 | 5.15 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 26 | 0 | 1 | 1 | 5.28 | .313 | 1.37 | 9.0 | 3.6 | 5.7 | 30.2 | 30 | 19 | 18 | 3 | 12 | 19 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 4.23 |