| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 24 | 24 | 9 | 10 | 3.64 | .283 | 1.15 | 7.2 | 3.2 | 8.3 | 170.2 | 136 | 69 | 69 | 19 | 61 | 156 | 1 | 0 | 0 | 0 | 17 | 5 | 3 | 3.78 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 79 | 23 | 23 | 6 | 8 | 5.81 | .335 | 1.50 | 10.0 | 3.6 | 4.3 | 159.2 | 177 | 107 | 103 | 31 | 63 | 76 | 1 | 0 | 0 | 0 | 9 | 1 | 1 | 5.79 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 23 | 23 | 9 | 10 | 4.80 | .317 | 1.37 | 9.5 | 2.9 | 5.8 | 172.1 | 181 | 93 | 92 | 16 | 55 | 110 | 6 | 0 | 0 | 2 | 9 | 4 | 2 | 3.96 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 22 | 22 | 8 | 10 | 3.80 | .274 | 1.11 | 8.1 | 1.9 | 3.9 | 187.1 | 168 | 84 | 79 | 23 | 40 | 80 | 12 | 0 | 0 | 2 | 10 | 4 | 1 | 4.45 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 62 | 0 | 7 | 8 | 3.75 | .290 | 1.18 | 7.1 | 3.6 | 9.1 | 74.1 | 58 | 32 | 31 | 5 | 30 | 75 | 0 | 8 | 4 | 0 | 0 | 3 | 3 | 3.19 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 54 | 0 | 2 | 2 | 3.83 | .330 | 1.48 | 9.0 | 4.4 | 9.0 | 49.1 | 49 | 24 | 21 | 9 | 24 | 49 | 0 | 9 | 2 | 0 | 0 | 0 | 1 | 4.86 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |