| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 22 | 22 | 6 | 6 | 3.10 | .265 | 1.06 | 6.7 | 2.9 | 8.0 | 162.2 | 120 | 59 | 56 | 11 | 52 | 144 | 1 | 0 | 0 | 0 | 16 | 4 | 2 | 3.14 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 21 | 21 | 7 | 7 | 4.36 | .321 | 1.41 | 9.8 | 3.0 | 4.3 | 144.1 | 156 | 71 | 70 | 16 | 48 | 68 | 1 | 0 | 0 | 0 | 11 | 1 | 3 | 4.52 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 19 | 19 | 3 | 9 | 4.38 | .322 | 1.38 | 9.3 | 3.1 | 3.9 | 123.1 | 127 | 66 | 60 | 4 | 43 | 53 | 0 | 0 | 0 | 0 | 10 | 6 | 2 | 3.76 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 19 | 19 | 4 | 10 | 4.65 | .324 | 1.42 | 9.0 | 3.8 | 4.3 | 124.0 | 124 | 69 | 64 | 15 | 52 | 59 | 3 | 0 | 0 | 0 | 11 | 2 | 0 | 4.93 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 56 | 0 | 5 | 3 | 3.28 | .267 | 1.05 | 7.5 | 1.9 | 8.9 | 74.0 | 62 | 28 | 27 | 7 | 16 | 73 | 0 | 8 | 2 | 0 | 0 | 3 | 1 | 3.03 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 46 | 0 | 4 | 4 | 4.05 | .307 | 1.26 | 8.0 | 3.5 | 9.2 | 46.2 | 41 | 23 | 21 | 6 | 18 | 47 | 0 | 6 | 5 | 0 | 0 | 3 | 6 | 4.02 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 33 | 0 | 4 | 3 | 4.46 | .335 | 1.49 | 7.8 | 5.8 | 8.0 | 36.1 | 31 | 18 | 18 | 1 | 23 | 32 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.58 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 27 | 0 | 0 | 3 | 5.85 | .349 | 1.61 | 12.1 | 2.5 | 7.9 | 32.1 | 43 | 21 | 21 | 8 | 9 | 28 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 5.34 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 3 | 1 | 1 | 1 | 4.26 | .283 | 1.18 | 7.5 | 3.8 | 3.8 | 12.2 | 10 | 6 | 6 | 1 | 5 | 5 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 4.50 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 18 | 1 | 4 | 1 | 4.82 | .311 | 1.36 | 7.4 | 4.8 | 7.4 | 28.0 | 23 | 15 | 15 | 4 | 15 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.82 |