| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 17 | 17 | 11 | 5 | 3.17 | .275 | 1.09 | 7.1 | 2.7 | 7.5 | 122.0 | 96 | 43 | 43 | 10 | 37 | 101 | 2 | 0 | 0 | 2 | 11 | 6 | 1 | 3.47 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 16 | 16 | 8 | 4 | 3.49 | .304 | 1.29 | 7.9 | 3.8 | 5.1 | 121.1 | 106 | 47 | 47 | 13 | 51 | 68 | 2 | 0 | 0 | 1 | 12 | 2 | 0 | 4.59 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 37 | 0 | 4 | 2 | 3.44 | .259 | 1.05 | 6.4 | 3.1 | 9.4 | 49.2 | 35 | 19 | 19 | 8 | 17 | 51 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 4.08 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 22 | 0 | 0 | 1 | 4.44 | .330 | 1.48 | 9.4 | 4.1 | 10.1 | 24.1 | 25 | 12 | 12 | 5 | 11 | 27 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.83 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 14 | 0 | 1 | 1 | 1.46 | .315 | 1.38 | 9.8 | 3.0 | 6.0 | 12.1 | 13 | 2 | 2 | 1 | 4 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 2 | 0 | 1 | 0 | 0.00 | .143 | 0.50 | 4.5 | 0.0 | 4.5 | 2.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.00 |