| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 17 | 17 | 11 | 3 | 3.04 | .261 | 1.05 | 6.7 | 2.8 | 8.4 | 109.2 | 81 | 39 | 37 | 4 | 34 | 102 | 1 | 0 | 0 | 1 | 13 | 1 | 0 | 2.57 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 85 | 16 | 16 | 8 | 6 | 3.43 | .297 | 1.24 | 8.8 | 2.4 | 4.7 | 102.1 | 100 | 46 | 39 | 9 | 27 | 53 | 3 | 0 | 0 | 2 | 9 | 3 | 2 | 3.99 |
| SP | Maddux, G.Maddux, Greg † # >> | 29 | 1995 | R | 89 | 17 | 17 | 10 | 3 | 3.15 | .242 | 0.94 | 6.9 | 1.6 | 6.0 | 131.1 | 100 | 46 | 46 | 10 | 24 | 87 | 3 | 0 | 0 | 1 | 11 | 2 | 3 | 3.26 |
| SP | Fernandez, S.Fernandez, Sid >> | 26 | 1988 | L | 50 | 16 | 16 | 7 | 3 | 4.26 | .301 | 1.26 | 6.9 | 4.5 | 8.5 | 95.0 | 73 | 48 | 45 | 7 | 47 | 90 | 0 | 0 | 0 | 0 | 9 | 3 | 3 | 3.64 |
| RP | Kimbrel, C.Kimbrel, Craig $ >> | 24 | 2012 | R | 100 | 49 | 0 | 0 | 4 | 2.88 | .248 | 0.97 | 5.4 | 3.5 | 9.8 | 65.2 | 39 | 21 | 21 | 6 | 25 | 71 | 0 | 12 | 2 | 0 | 0 | 1 | 3 | 3.22 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 27 | 0 | 4 | 3 | 1.78 | .242 | 0.92 | 5.7 | 2.7 | 8.7 | 30.1 | 19 | 6 | 6 | 3 | 9 | 29 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.37 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 15 | 0 | 2 | 0 | 1.08 | .180 | 0.66 | 3.4 | 2.8 | 11.8 | 16.2 | 6 | 2 | 2 | 1 | 5 | 21 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 2.13 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 15 | 0 | 1 | 0 | 2.61 | .273 | 1.10 | 6.7 | 3.2 | 4.6 | 31.0 | 23 | 10 | 9 | 1 | 11 | 16 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.55 |