| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 18 | 18 | 8 | 3 | 3.93 | .326 | 1.44 | 7.6 | 5.5 | 9.4 | 107.2 | 90 | 49 | 47 | 9 | 65 | 112 | 0 | 0 | 0 | 0 | 10 | 1 | 4 | 3.85 |
| SP | Penny, B.Penny, Brad # >> | 23 | 2001 | R | 42 | 17 | 17 | 3 | 10 | 5.62 | .344 | 1.54 | 10.5 | 3.4 | 6.5 | 107.1 | 125 | 72 | 67 | 16 | 40 | 77 | 1 | 0 | 0 | 0 | 7 | 4 | 1 | 4.74 |
| SP | Miller, W.Miller, Wade >> | 25 | 2001 | R | 28 | 17 | 17 | 3 | 6 | 6.23 | .370 | 1.74 | 10.4 | 5.3 | 6.3 | 95.1 | 110 | 69 | 66 | 17 | 56 | 67 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 5.75 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 94 | 57 | 0 | 2 | 4 | 5.56 | .324 | 1.39 | 10.3 | 2.3 | 8.9 | 79.1 | 90 | 50 | 49 | 14 | 20 | 78 | 0 | 7 | 3 | 0 | 0 | 4 | 5 | 4.24 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 41 | 39 | 0 | 1 | 4 | 4.37 | .300 | 1.27 | 9.6 | 1.9 | 6.5 | 47.1 | 50 | 23 | 23 | 7 | 10 | 34 | 0 | 7 | 1 | 0 | 0 | 1 | 1 | 4.19 |
| RP | Wickman, B.Wickman, Bob >> | 32 | 2001 | R | 15 | 29 | 0 | 1 | 4 | 3.75 | .308 | 1.22 | 7.3 | 3.8 | 9.3 | 36.0 | 29 | 15 | 15 | 3 | 15 | 37 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 3.61 |