| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 99 | 14 | 14 | 7 | 3 | 4.18 | .287 | 1.20 | 8.2 | 2.6 | 8.7 | 92.2 | 84 | 46 | 43 | 17 | 27 | 89 | 2 | 0 | 0 | 0 | 8 | 1 | 5 | 4.38 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 88 | 14 | 14 | 3 | 4 | 7.08 | .354 | 1.63 | 11.9 | 2.9 | 8.7 | 68.2 | 90 | 57 | 54 | 16 | 22 | 66 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 5.13 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 14 | 14 | 5 | 3 | 4.96 | .337 | 1.49 | 9.8 | 3.6 | 7.0 | 78.0 | 85 | 46 | 43 | 18 | 31 | 61 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 5.74 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 57 | 15 | 14 | 4 | 4 | 7.84 | .393 | 1.93 | 14.5 | 2.8 | 7.1 | 70.0 | 113 | 68 | 61 | 20 | 22 | 55 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 6.13 |
| RP | Dotel, O.Dotel, Octavio $ >> | 29 | 2002 | R | 88 | 41 | 0 | 4 | 2 | 2.09 | .290 | 1.14 | 6.5 | 3.8 | 10.3 | 47.1 | 34 | 13 | 11 | 4 | 20 | 54 | 0 | 1 | 1 | 0 | 0 | 4 | 0 | 3.34 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 75 | 41 | 0 | 0 | 1 | 3.95 | .309 | 1.32 | 9.2 | 2.6 | 7.2 | 41.0 | 42 | 21 | 18 | 2 | 12 | 33 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 2.98 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 28 | 0 | 2 | 2 | 5.16 | .370 | 1.68 | 9.8 | 5.7 | 9.4 | 22.2 | 24 | 14 | 13 | 9 | 14 | 23 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 8.41 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 21 | 0 | 1 | 1 | 4.03 | .337 | 1.48 | 6.1 | 7.4 | 7.8 | 22.1 | 15 | 11 | 10 | 3 | 18 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.64 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 62 | 41 | 0 | 5 | 0 | 4.45 | .274 | 1.13 | 6.1 | 4.2 | 7.4 | 28.1 | 19 | 14 | 14 | 5 | 13 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.07 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 54 | 31 | 0 | 0 | 0 | 4.67 | .278 | 1.10 | 7.4 | 2.6 | 10.1 | 17.1 | 14 | 9 | 9 | 4 | 5 | 19 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.88 |
| SU | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 27 | 0 | 0 | 1 | 5.93 | .344 | 1.57 | 7.0 | 7.3 | 11.3 | 27.1 | 21 | 18 | 18 | 4 | 22 | 34 | 0 | 1 | 4 | 0 | 0 | 0 | 2 | 4.85 |