| SP | Santana, J.Santana, Johan $ >> | 25 | 2004 | L | 100 | 20 | 20 | 8 | 6 | 4.13 | .319 | 1.37 | 9.2 | 3.2 | 9.6 | 117.2 | 119 | 55 | 54 | 13 | 42 | 125 | 2 | 0 | 0 | 1 | 12 | 4 | 7 | 3.49 |
| SP | Pettitte, A.Pettitte, Andy † # >> | 33 | 2005 | L | 78 | 18 | 18 | 11 | 5 | 3.32 | .252 | 1.01 | 7.4 | 1.7 | 6.3 | 127.1 | 105 | 51 | 47 | 26 | 24 | 89 | 2 | 0 | 0 | 0 | 11 | 0 | 2 | 4.83 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 71 | 18 | 18 | 4 | 7 | 6.58 | .370 | 1.73 | 10.9 | 4.7 | 6.5 | 90.1 | 109 | 69 | 66 | 14 | 47 | 65 | 0 | 0 | 0 | 0 | 3 | 3 | 3 | 5.24 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 60 | 17 | 17 | 5 | 5 | 6.28 | .350 | 1.56 | 9.9 | 4.1 | 8.1 | 86.0 | 95 | 60 | 60 | 13 | 39 | 77 | 0 | 0 | 0 | 0 | 4 | 5 | 3 | 4.71 |
| RP | Dotel, O.Dotel, Octavio $ >> | 29 | 2002 | R | 89 | 49 | 0 | 2 | 1 | 2.48 | .280 | 1.15 | 7.1 | 3.4 | 11.8 | 61.2 | 48 | 20 | 17 | 4 | 23 | 80 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 2.41 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 46 | 0 | 4 | 2 | 3.19 | .280 | 1.15 | 7.3 | 3.0 | 7.7 | 48.0 | 39 | 17 | 17 | 4 | 16 | 41 | 0 | 3 | 3 | 0 | 0 | 1 | 2 | 3.44 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 69 | 28 | 0 | 4 | 2 | 4.40 | .352 | 1.60 | 9.6 | 5.1 | 9.0 | 30.2 | 32 | 16 | 15 | 6 | 17 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 5.40 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 20 | 0 | 2 | 2 | 4.57 | .286 | 1.20 | 7.7 | 3.4 | 8.6 | 21.2 | 18 | 11 | 11 | 3 | 8 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.10 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 61 | 16 | 0 | 0 | 0 | 4.15 | .297 | 1.27 | 6.9 | 4.8 | 8.5 | 17.1 | 13 | 8 | 8 | 3 | 9 | 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 33 | 0 | 1 | 0 | 6.33 | .340 | 1.55 | 7.7 | 6.4 | 7.7 | 21.1 | 18 | 16 | 15 | 2 | 15 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.67 |
| RP | Takatsu, S.Takatsu, Shingo >> | 36 | 2004 | R | 56 | 16 | 0 | 1 | 0 | 1.53 | .264 | 1.02 | 4.2 | 5.3 | 6.9 | 17.2 | 8 | 3 | 3 | 0 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.41 |
| SU | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 33 | 0 | 1 | 1 | 4.12 | .293 | 1.17 | 6.0 | 4.6 | 10.4 | 39.1 | 26 | 18 | 18 | 4 | 20 | 45 | 0 | 4 | 4 | 0 | 0 | 3 | 2 | 3.79 |
| CL | Saito, T.Saito, Takashi † >> | 37 | 2007 | R | 100 | 36 | 0 | 4 | 3 | 3.22 | .310 | 1.32 | 8.5 | 3.5 | 10.0 | 36.1 | 34 | 14 | 13 | 4 | 14 | 40 | 0 | 22 | 2 | 0 | 0 | 1 | 0 | 3.47 |