| SP | Lincecum, T.Lincecum, Tim $$ >> | 25 | 2009 | R | 92 | 34 | 34 | 12 | 12 | 4.51 | .337 | 1.50 | 9.9 | 3.7 | 8.9 | 219.1 | 241 | 111 | 110 | 29 | 89 | 217 | 1 | 0 | 0 | 0 | 18 | 5 | 6 | 4.03 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 32 | 32 | 8 | 13 | 5.79 | .331 | 1.46 | 10.4 | 2.8 | 7.4 | 183.1 | 212 | 130 | 118 | 30 | 56 | 150 | 1 | 0 | 0 | 1 | 15 | 4 | 8 | 4.48 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 60 | 32 | 31 | 7 | 13 | 6.23 | .368 | 1.72 | 11.9 | 3.6 | 6.5 | 179.0 | 237 | 133 | 124 | 28 | 71 | 129 | 0 | 0 | 0 | 0 | 12 | 5 | 4 | 4.87 |
| CL | Balfour, G.Balfour, Grant † $ >> | 31 | 2008 | R | 90 | 73 | 0 | 3 | 6 | 4.79 | .327 | 1.45 | 6.4 | 6.7 | 11.1 | 73.1 | 52 | 39 | 39 | 9 | 54 | 90 | 0 | 40 | 4 | 0 | 0 | 1 | 2 | 4.40 |
| SU | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 87 | 85 | 0 | 4 | 1 | 3.17 | .271 | 1.10 | 7.5 | 2.5 | 9.6 | 99.1 | 82 | 40 | 35 | 8 | 27 | 106 | 0 | 2 | 8 | 0 | 0 | 2 | 0 | 2.79 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 88 | 89 | 0 | 5 | 5 | 5.69 | .380 | 1.83 | 11.6 | 4.9 | 6.4 | 98.0 | 126 | 65 | 62 | 13 | 53 | 70 | 0 | 2 | 4 | 0 | 0 | 1 | 2 | 4.95 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 72 | 0 | 10 | 3 | 5.60 | .359 | 1.62 | 11.1 | 3.5 | 7.7 | 90.0 | 111 | 59 | 56 | 17 | 35 | 77 | 0 | 3 | 2 | 0 | 0 | 5 | 0 | 5.08 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 50 | 0 | 2 | 2 | 5.92 | .372 | 1.70 | 10.1 | 5.5 | 7.9 | 51.2 | 57 | 35 | 34 | 10 | 31 | 45 | 0 | 1 | 0 | 0 | 0 | 4 | 1 | 5.84 |