| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 18 | 18 | 6 | 6 | 3.93 | .312 | 1.33 | 9.5 | 2.5 | 6.9 | 119.0 | 125 | 57 | 52 | 17 | 33 | 91 | 0 | 0 | 0 | 0 | 11 | 4 | 4 | 4.26 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 87 | 17 | 17 | 5 | 6 | 4.67 | .312 | 1.33 | 9.2 | 2.8 | 9.2 | 111.2 | 113 | 63 | 58 | 25 | 35 | 114 | 2 | 0 | 0 | 0 | 7 | 4 | 1 | 4.93 |
| SP | Williams, W.Williams, Woody † # >> | 36 | 2002 | R | 79 | 17 | 17 | 11 | 4 | 2.78 | .244 | 0.91 | 6.4 | 1.8 | 7.3 | 116.2 | 83 | 36 | 36 | 10 | 23 | 94 | 1 | 0 | 0 | 1 | 11 | 7 | 1 | 3.28 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 16 | 16 | 8 | 3 | 4.68 | .300 | 1.24 | 9.3 | 1.9 | 6.3 | 105.2 | 109 | 55 | 55 | 18 | 22 | 74 | 1 | 0 | 0 | 1 | 8 | 5 | 0 | 4.59 |
| RP | Wagner, B.Wagner, Billy $ >> | 32 | 2003 | L | 89 | 47 | 0 | 1 | 2 | 6.94 | .314 | 1.38 | 9.3 | 3.3 | 9.0 | 36.1 | 37 | 28 | 28 | 8 | 13 | 36 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.97 |
| CL | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 97 | 34 | 0 | 3 | 4 | 4.72 | .352 | 1.57 | 9.0 | 5.3 | 8.2 | 34.1 | 34 | 20 | 18 | 4 | 20 | 31 | 0 | 21 | 5 | 0 | 0 | 2 | 0 | 4.65 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 29 | 0 | 1 | 0 | 6.85 | .343 | 1.52 | 10.2 | 3.7 | 5.3 | 22.1 | 25 | 18 | 17 | 7 | 9 | 13 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 7.32 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 50 | 25 | 0 | 1 | 1 | 4.30 | .313 | 1.33 | 9.6 | 2.5 | 10.2 | 29.1 | 31 | 14 | 14 | 5 | 8 | 33 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.90 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 55 | 16 | 0 | 3 | 1 | 6.00 | .372 | 1.76 | 11.6 | 4.2 | 6.4 | 45.0 | 58 | 33 | 30 | 12 | 21 | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6.51 |