| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 16 | 16 | 9 | 3 | 3.25 | .278 | 1.11 | 7.1 | 2.9 | 9.9 | 110.2 | 87 | 42 | 40 | 16 | 36 | 121 | 1 | 0 | 0 | 0 | 10 | 5 | 1 | 3.81 |
| SP | Carpenter, C.Carpenter, Chris # >> | 34 | 2009 | R | 80 | 16 | 16 | 3 | 5 | 8.12 | .374 | 1.75 | 12.4 | 3.4 | 6.8 | 85.1 | 117 | 81 | 77 | 17 | 32 | 64 | 1 | 0 | 0 | 0 | 3 | 4 | 2 | 5.36 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 16 | 16 | 3 | 8 | 5.56 | .352 | 1.60 | 10.9 | 3.6 | 8.7 | 90.2 | 109 | 59 | 56 | 9 | 36 | 87 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 3.67 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 75 | 16 | 16 | 9 | 3 | 3.67 | .316 | 1.35 | 8.1 | 4.0 | 9.4 | 105.1 | 95 | 46 | 43 | 13 | 47 | 110 | 0 | 0 | 0 | 0 | 9 | 4 | 4 | 3.97 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 59 | 16 | 16 | 4 | 3 | 5.82 | .343 | 1.53 | 10.7 | 3.1 | 7.3 | 85.0 | 101 | 58 | 55 | 13 | 29 | 69 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 4.49 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 36 | 0 | 2 | 3 | 2.72 | .287 | 1.21 | 7.8 | 3.2 | 9.2 | 39.2 | 34 | 12 | 12 | 3 | 14 | 40 | 0 | 23 | 3 | 0 | 0 | 0 | 0 | 3.03 |
| SU | Gordon, T.Gordon, Tom $ >> | 37 | 2004 | R | 81 | 34 | 0 | 3 | 1 | 2.56 | .275 | 1.04 | 6.4 | 3.2 | 8.1 | 31.2 | 22 | 10 | 9 | 1 | 11 | 28 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 2.97 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 86 | 38 | 0 | 3 | 1 | 3.15 | .283 | 1.18 | 10.0 | 0.8 | 8.8 | 45.2 | 50 | 19 | 16 | 7 | 4 | 44 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 64 | 41 | 0 | 2 | 2 | 2.89 | .253 | 1.02 | 7.8 | 1.5 | 7.5 | 37.1 | 32 | 12 | 12 | 2 | 6 | 31 | 0 | 0 | 3 | 0 | 0 | 0 | 2 | 2.51 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 27 | 0 | 2 | 1 | 5.21 | .313 | 1.32 | 6.6 | 5.2 | 9.5 | 19.0 | 14 | 15 | 11 | 4 | 11 | 20 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.53 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 48 | 38 | 0 | 3 | 1 | 5.68 | .362 | 1.67 | 10.2 | 5.2 | 8.7 | 31.2 | 35 | 20 | 20 | 11 | 18 | 30 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 7.52 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 28 | 0 | 1 | 1 | 7.23 | .309 | 1.34 | 11.0 | 1.5 | 7.5 | 18.2 | 22 | 16 | 15 | 7 | 3 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.89 |