| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 28 | 28 | 6 | 16 | 4.82 | .318 | 1.39 | 8.6 | 3.9 | 8.5 | 177.1 | 170 | 103 | 95 | 28 | 77 | 168 | 2 | 0 | 0 | 0 | 16 | 1 | 5 | 4.48 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 60 | 26 | 26 | 10 | 8 | 4.30 | .293 | 1.23 | 8.4 | 2.8 | 5.3 | 169.2 | 157 | 83 | 81 | 16 | 52 | 100 | 0 | 0 | 0 | 0 | 13 | 2 | 5 | 4.01 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 26 | 26 | 4 | 14 | 7.19 | .368 | 1.72 | 11.0 | 4.5 | 9.0 | 101.1 | 123 | 83 | 81 | 23 | 51 | 101 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.56 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 76 | 0 | 5 | 5 | 2.84 | .265 | 1.06 | 6.6 | 2.9 | 7.5 | 111.0 | 82 | 39 | 35 | 8 | 36 | 92 | 0 | 4 | 4 | 0 | 0 | 2 | 2 | 3.31 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 62 | 0 | 5 | 4 | 4.56 | .311 | 1.32 | 6.1 | 5.8 | 8.9 | 71.0 | 48 | 36 | 36 | 6 | 46 | 70 | 0 | 6 | 1 | 0 | 0 | 2 | 2 | 4.15 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 51 | 0 | 2 | 3 | 4.34 | .283 | 1.15 | 8.3 | 2.1 | 5.8 | 64.1 | 59 | 31 | 31 | 12 | 15 | 41 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.95 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 9 | 0 | 2 | 1 | 10.26 | .405 | 2.04 | 15.8 | 3.4 | 5.1 | 16.2 | 28 | 19 | 19 | 6 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.88 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 33 | 0 | 1 | 5 | 4.30 | .332 | 1.49 | 7.4 | 6.0 | 4.3 | 67.0 | 55 | 35 | 32 | 10 | 45 | 32 | 0 | 4 | 2 | 0 | 0 | 0 | 2 | 6.00 |