| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 8 | 14 | 3.42 | .295 | 1.24 | 8.5 | 2.6 | 8.0 | 236.2 | 224 | 99 | 90 | 29 | 69 | 209 | 5 | 0 | 0 | 1 | 21 | 4 | 0 | 3.75 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 33 | 33 | 10 | 18 | 5.10 | .314 | 1.34 | 9.4 | 2.7 | 4.6 | 243.2 | 254 | 151 | 138 | 35 | 72 | 124 | 11 | 0 | 0 | 3 | 12 | 8 | 9 | 4.84 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 32 | 32 | 18 | 11 | 3.64 | .306 | 1.28 | 7.8 | 3.8 | 6.0 | 237.2 | 206 | 106 | 96 | 20 | 99 | 159 | 8 | 0 | 0 | 4 | 19 | 10 | 3 | 4.14 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 31 | 31 | 5 | 16 | 6.16 | .355 | 1.62 | 10.2 | 4.4 | 4.4 | 175.1 | 198 | 122 | 120 | 22 | 86 | 86 | 0 | 0 | 0 | 0 | 10 | 6 | 3 | 5.23 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 86 | 0 | 7 | 2 | 3.98 | .310 | 1.33 | 7.7 | 4.2 | 9.1 | 113.0 | 97 | 55 | 50 | 12 | 53 | 114 | 0 | 11 | 4 | 0 | 0 | 2 | 3 | 3.82 |
| RP | Dotel, O.Dotel, Octavio # >> | 29 | 2002 | R | 68 | 74 | 0 | 4 | 3 | 5.16 | .347 | 1.59 | 10.1 | 4.2 | 8.2 | 82.0 | 92 | 48 | 47 | 10 | 38 | 75 | 0 | 10 | 4 | 0 | 0 | 1 | 3 | 4.18 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 35 | 0 | 2 | 3 | 4.34 | .313 | 1.32 | 8.4 | 3.5 | 8.2 | 64.1 | 60 | 33 | 31 | 6 | 25 | 58 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 3.72 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 47 | 2 | 0 | 0 | 0 | 8.10 | .375 | 1.80 | 15.0 | 3.0 | 0.0 | 3.1 | 5 | 3 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.67 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 55 | 16 | 1 | 6 | 3 | 4.70 | .319 | 1.37 | 9.0 | 3.6 | 6.9 | 30.2 | 30 | 17 | 16 | 2 | 12 | 23 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.63 |