| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 28 | 28 | 9 | 13 | 4.30 | .301 | 1.27 | 8.6 | 2.8 | 9.2 | 171.2 | 164 | 90 | 82 | 20 | 54 | 174 | 0 | 0 | 0 | 0 | 16 | 4 | 0 | 3.50 |
| SP | Gibson, B.Gibson, Bob $$ >> | 33 | 1968 | R | 93 | 27 | 27 | 13 | 11 | 3.45 | .274 | 1.11 | 7.4 | 2.7 | 6.0 | 198.1 | 162 | 78 | 76 | 18 | 59 | 131 | 6 | 0 | 0 | 2 | 16 | 4 | 4 | 3.81 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 27 | 27 | 11 | 8 | 3.63 | .303 | 1.30 | 8.1 | 3.6 | 5.0 | 190.2 | 171 | 88 | 77 | 15 | 76 | 106 | 3 | 0 | 0 | 0 | 17 | 2 | 5 | 4.14 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 26 | 26 | 9 | 10 | 4.53 | .309 | 1.32 | 9.5 | 2.3 | 4.2 | 177.0 | 187 | 96 | 89 | 21 | 46 | 83 | 5 | 0 | 0 | 1 | 11 | 4 | 1 | 4.45 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 25 | 25 | 7 | 9 | 5.34 | .348 | 1.59 | 9.6 | 4.7 | 5.6 | 155.0 | 165 | 96 | 92 | 21 | 81 | 96 | 1 | 0 | 0 | 0 | 11 | 2 | 5 | 5.13 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 48 | 0 | 1 | 5 | 3.51 | .274 | 1.11 | 8.1 | 2.1 | 7.9 | 48.2 | 43 | 19 | 19 | 7 | 11 | 42 | 0 | 29 | 5 | 0 | 0 | 1 | 0 | 3.90 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 39 | 0 | 2 | 8 | 6.10 | .333 | 1.50 | 8.3 | 5.3 | 6.6 | 41.1 | 38 | 28 | 28 | 3 | 24 | 30 | 0 | 5 | 11 | 0 | 0 | 0 | 2 | 4.24 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 57 | 0 | 3 | 1 | 3.96 | .295 | 1.22 | 7.5 | 3.5 | 10.2 | 61.1 | 51 | 33 | 27 | 8 | 24 | 69 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 3.72 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 20 | 0 | 1 | 2 | 3.22 | .295 | 1.25 | 7.0 | 4.5 | 9.0 | 22.1 | 17 | 8 | 8 | 3 | 11 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.27 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 0 | 2 | 1 | 4.77 | .320 | 1.37 | 9.3 | 3.2 | 3.2 | 54.2 | 56 | 29 | 29 | 4 | 19 | 19 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.43 |