| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 38 | 38 | 20 | 14 | 4.01 | .305 | 1.29 | 8.7 | 2.9 | 7.7 | 269.1 | 259 | 129 | 120 | 22 | 88 | 230 | 4 | 0 | 0 | 2 | 18 | 7 | 7 | 3.41 |
| SP | Leonard, D.Leonard, Dutch $$ >> | 22 | 1914 | L | 91 | 36 | 36 | 20 | 10 | 3.17 | .275 | 1.12 | 6.7 | 3.3 | 5.3 | 250.0 | 187 | 91 | 88 | 23 | 93 | 147 | 2 | 0 | 0 | 0 | 24 | 5 | 3 | 4.20 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 34 | 34 | 16 | 6 | 3.84 | .302 | 1.28 | 7.9 | 3.7 | 6.5 | 234.2 | 205 | 111 | 100 | 13 | 95 | 170 | 3 | 0 | 0 | 1 | 21 | 5 | 4 | 3.55 |
| SP | Maddux, G.Maddux, Greg $ >> | 29 | 1995 | R | 89 | 34 | 34 | 18 | 10 | 3.46 | .283 | 1.17 | 8.5 | 2.0 | 5.3 | 260.0 | 245 | 107 | 100 | 24 | 58 | 153 | 10 | 0 | 0 | 5 | 20 | 5 | 5 | 3.75 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 84 | 31 | 31 | 17 | 9 | 4.05 | .297 | 1.25 | 8.6 | 2.7 | 8.0 | 213.1 | 204 | 97 | 96 | 24 | 63 | 189 | 4 | 0 | 0 | 2 | 17 | 4 | 3 | 3.63 |
| RP | Eckersley, D.Eckersley, Dennis $ >> | 36 | 1990 | R | 88 | 84 | 0 | 7 | 2 | 2.34 | .285 | 1.16 | 7.4 | 3.0 | 8.2 | 77.0 | 63 | 21 | 20 | 5 | 26 | 70 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 3.16 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 77 | 59 | 0 | 5 | 3 | 3.61 | .245 | 0.96 | 5.2 | 3.5 | 7.6 | 52.1 | 30 | 22 | 21 | 8 | 20 | 44 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.52 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 37 | 0 | 6 | 2 | 3.10 | .295 | 1.25 | 6.5 | 5.0 | 6.3 | 40.2 | 29 | 14 | 14 | 3 | 22 | 28 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.23 |
| CL | Chapman, A.Chapman, Aroldis † $$ >> | 37 | 2025 | L | 96 | 67 | 0 | 1 | 2 | 2.27 | .237 | 0.93 | 5.6 | 2.9 | 7.3 | 63.1 | 39 | 19 | 16 | 7 | 20 | 51 | 0 | 57 | 4 | 0 | 0 | 0 | 1 | 3.78 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 14 | 1 | 5 | 0 | 2.96 | .277 | 1.15 | 6.4 | 4.1 | 9.9 | 48.2 | 34 | 17 | 16 | 5 | 22 | 53 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.52 |