| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 30 | 30 | 8 | 11 | 4.98 | .337 | 1.51 | 10.0 | 3.6 | 7.8 | 157.1 | 175 | 93 | 87 | 23 | 63 | 136 | 0 | 0 | 0 | 0 | 13 | 2 | 2 | 4.41 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 29 | 29 | 10 | 11 | 4.07 | .300 | 1.25 | 8.7 | 2.6 | 4.8 | 197.0 | 190 | 100 | 89 | 18 | 57 | 104 | 6 | 0 | 0 | 0 | 14 | 6 | 5 | 4.09 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 82 | 28 | 28 | 12 | 6 | 2.99 | .273 | 1.12 | 8.0 | 2.0 | 4.4 | 207.2 | 185 | 76 | 69 | 15 | 47 | 102 | 3 | 0 | 0 | 1 | 20 | 2 | 3 | 3.67 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 28 | 28 | 9 | 13 | 5.47 | .317 | 1.38 | 9.3 | 3.1 | 6.7 | 163.0 | 169 | 104 | 99 | 25 | 56 | 122 | 3 | 0 | 0 | 2 | 10 | 2 | 4 | 4.56 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 71 | 27 | 27 | 10 | 6 | 3.60 | .277 | 1.13 | 7.5 | 2.7 | 5.1 | 172.1 | 143 | 74 | 69 | 17 | 52 | 98 | 1 | 0 | 0 | 1 | 15 | 3 | 5 | 4.10 |
| RP | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 82 | 0 | 8 | 2 | 2.33 | .242 | 0.95 | 5.6 | 3.0 | 8.8 | 108.1 | 67 | 28 | 28 | 8 | 36 | 105 | 0 | 11 | 7 | 0 | 0 | 1 | 7 | 3.05 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 66 | 0 | 7 | 5 | 4.00 | .287 | 1.20 | 7.0 | 3.8 | 5.3 | 81.0 | 63 | 37 | 36 | 12 | 34 | 48 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 5.04 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 52 | 0 | 5 | 1 | 3.68 | .305 | 1.29 | 7.7 | 4.0 | 9.6 | 63.2 | 54 | 26 | 26 | 6 | 28 | 67 | 0 | 4 | 3 | 0 | 0 | 2 | 7 | 3.54 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 46 | 0 | 2 | 2 | 2.65 | .261 | 1.02 | 5.5 | 3.8 | 8.4 | 57.2 | 35 | 17 | 17 | 5 | 24 | 53 | 0 | 7 | 0 | 0 | 0 | 2 | 1 | 3.65 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 31 | 0 | 5 | 4 | 3.55 | .278 | 1.16 | 7.1 | 3.3 | 9.5 | 38.0 | 30 | 15 | 15 | 10 | 14 | 40 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 5.42 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 31 | 0 | 1 | 1 | 3.34 | .302 | 1.27 | 7.6 | 3.9 | 8.7 | 32.1 | 27 | 14 | 12 | 7 | 14 | 31 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 5.31 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 9 | 1 | 2 | 2 | 3.10 | .265 | 1.08 | 6.3 | 3.6 | 5.0 | 20.1 | 14 | 7 | 7 | 3 | 8 | 11 | 1 | 2 | 0 | 0 | 1 | 0 | 0 | 5.05 |