| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 28 | 28 | 10 | 15 | 4.33 | .324 | 1.39 | 9.2 | 3.4 | 8.4 | 206.0 | 210 | 105 | 99 | 25 | 77 | 192 | 6 | 0 | 0 | 2 | 12 | 9 | 4 | 3.97 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 28 | 28 | 8 | 12 | 5.61 | .332 | 1.48 | 9.9 | 3.4 | 4.6 | 181.1 | 200 | 116 | 113 | 21 | 68 | 93 | 3 | 0 | 0 | 1 | 11 | 2 | 5 | 4.64 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 28 | 28 | 10 | 15 | 4.78 | .313 | 1.34 | 8.8 | 3.2 | 5.9 | 203.1 | 199 | 116 | 108 | 20 | 73 | 132 | 4 | 0 | 0 | 1 | 13 | 6 | 10 | 4.15 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 70 | 0 | 6 | 5 | 3.29 | .285 | 1.20 | 7.4 | 3.4 | 7.6 | 112.0 | 92 | 42 | 41 | 13 | 42 | 94 | 0 | 15 | 6 | 0 | 0 | 0 | 0 | 3.96 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 56 | 0 | 5 | 1 | 3.76 | .272 | 1.12 | 8.6 | 1.5 | 8.9 | 67.0 | 64 | 28 | 28 | 8 | 11 | 66 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 3.07 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 40 | 0 | 4 | 5 | 4.78 | .312 | 1.36 | 8.6 | 3.8 | 8.4 | 43.1 | 41 | 23 | 23 | 5 | 18 | 40 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.91 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 1 | 0 | 1 | 6.75 | .448 | 2.44 | 16.2 | 7.2 | 1.8 | 5.1 | 9 | 5 | 4 | 1 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.60 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 3 | 0 | 1 | 0 | 0.00 | .231 | 0.90 | 6.0 | 3.0 | 3.0 | 3.1 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 17 | 0 | 1 | 4 | 6.20 | .339 | 1.50 | 9.8 | 4.1 | 3.0 | 24.2 | 26 | 18 | 17 | 5 | 11 | 8 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 6.54 |