| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 11 | 11 | 3 | 5 | 2.62 | .265 | 1.08 | 7.3 | 2.4 | 6.4 | 86.0 | 70 | 25 | 25 | 6 | 23 | 61 | 4 | 0 | 0 | 1 | 8 | 0 | 1 | 3.29 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 11 | 11 | 5 | 4 | 5.16 | .329 | 1.47 | 10.2 | 3.0 | 6.4 | 68.0 | 77 | 39 | 39 | 10 | 23 | 48 | 1 | 0 | 0 | 0 | 4 | 0 | 1 | 4.51 |
| SP | Nolasco, R.Nolasco, Ricky # >> | 26 | 2008 | R | 56 | 11 | 11 | 7 | 3 | 3.38 | .287 | 1.19 | 9.2 | 1.6 | 8.1 | 74.2 | 76 | 28 | 28 | 10 | 13 | 67 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 3.51 |
| SP | Matsuzaka, D.Matsuzaka, Daisuke >> | 28 | 2008 | R | 34 | 11 | 11 | 1 | 5 | 7.91 | .399 | 1.95 | 9.4 | 8.4 | 7.4 | 46.2 | 48 | 42 | 41 | 6 | 43 | 38 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.98 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 31 | 0 | 4 | 2 | 2.15 | .296 | 1.22 | 8.2 | 2.7 | 9.6 | 46.0 | 42 | 14 | 11 | 4 | 14 | 49 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.04 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 61 | 22 | 0 | 2 | 1 | 3.65 | .308 | 1.30 | 8.3 | 3.8 | 9.4 | 24.2 | 22 | 10 | 10 | 4 | 10 | 25 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.46 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 45 | 15 | 0 | 0 | 0 | 3.92 | .253 | 1.02 | 5.9 | 3.6 | 9.0 | 20.2 | 13 | 9 | 9 | 2 | 8 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 3.50 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 34 | 17 | 0 | 1 | 1 | 3.45 | .382 | 1.85 | 10.8 | 6.6 | 9.6 | 15.2 | 18 | 7 | 6 | 3 | 11 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.67 |