| SP | Hernandez, F.Hernandez, Felix † # >> | 19 | 2005 | R | 96 | 28 | 28 | 14 | 12 | 4.13 | .275 | 1.11 | 7.6 | 2.4 | 8.0 | 204.2 | 173 | 95 | 94 | 33 | 55 | 181 | 7 | 0 | 0 | 2 | 15 | 5 | 4 | 4.21 |
| SP | Burnett, A.Burnett, A.J. >> | 25 | 2002 | R | 57 | 26 | 26 | 10 | 10 | 5.94 | .354 | 1.61 | 9.8 | 4.7 | 6.9 | 150.0 | 163 | 101 | 99 | 18 | 79 | 115 | 0 | 0 | 0 | 0 | 11 | 5 | 7 | 4.71 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 26 | 26 | 6 | 17 | 5.03 | .338 | 1.49 | 10.4 | 3.0 | 6.9 | 161.0 | 186 | 93 | 90 | 32 | 54 | 124 | 3 | 0 | 0 | 0 | 12 | 7 | 0 | 5.18 |
| CL | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 96 | 44 | 0 | 3 | 3 | 1.88 | .213 | 0.79 | 5.7 | 1.5 | 10.5 | 43.0 | 27 | 9 | 9 | 2 | 7 | 50 | 0 | 34 | 2 | 0 | 0 | 1 | 1 | 1.84 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 74 | 79 | 0 | 1 | 2 | 4.24 | .304 | 1.28 | 9.3 | 2.3 | 8.6 | 68.0 | 70 | 32 | 32 | 9 | 17 | 65 | 0 | 0 | 2 | 0 | 0 | 2 | 4 | 3.65 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 61 | 0 | 5 | 0 | 2.66 | .272 | 1.08 | 5.9 | 3.8 | 11.1 | 47.1 | 31 | 17 | 14 | 6 | 20 | 58 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 3.60 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 54 | 68 | 0 | 0 | 0 | 3.96 | .270 | 1.11 | 5.7 | 4.5 | 8.8 | 38.2 | 24 | 17 | 17 | 7 | 19 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.95 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 71 | 31 | 0 | 3 | 0 | 1.14 | .245 | 0.89 | 6.3 | 2.0 | 7.4 | 23.2 | 16 | 4 | 3 | 1 | 5 | 19 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 2.83 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 73 | 11 | 0 | 0 | 1 | 9.82 | .411 | 2.00 | 9.8 | 8.2 | 9.0 | 11.0 | 12 | 12 | 12 | 1 | 10 | 11 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 5.18 |