| SP | Schilling, C.Schilling, Curt † >> | 36 | 2002 | R | 93 | 35 | 35 | 20 | 11 | 3.38 | .291 | 1.19 | 8.7 | 2.0 | 8.9 | 253.1 | 245 | 97 | 95 | 29 | 56 | 250 | 8 | 0 | 0 | 2 | 23 | 11 | 5 | 3.31 |
| SP | Young, C.Young, Chris $$ >> | 28 | 2007 | R | 82 | 34 | 34 | 15 | 10 | 4.06 | .300 | 1.25 | 7.4 | 3.9 | 6.7 | 201.2 | 166 | 93 | 91 | 21 | 86 | 149 | 0 | 0 | 0 | 0 | 18 | 7 | 5 | 4.26 |
| SP | Duchscherer, J.Duchscherer, Justin # >> | 31 | 2008 | R | 85 | 33 | 33 | 19 | 10 | 4.25 | .292 | 1.22 | 8.4 | 2.5 | 6.0 | 216.0 | 202 | 103 | 102 | 34 | 61 | 144 | 4 | 0 | 0 | 1 | 19 | 4 | 3 | 4.62 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 33 | 33 | 11 | 13 | 4.84 | .331 | 1.45 | 8.8 | 4.2 | 6.5 | 208.1 | 204 | 116 | 112 | 25 | 98 | 151 | 2 | 0 | 0 | 0 | 14 | 7 | 4 | 4.63 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 84 | 71 | 0 | 3 | 3 | 3.31 | .279 | 1.14 | 5.4 | 4.9 | 9.0 | 84.1 | 50 | 33 | 31 | 11 | 46 | 84 | 0 | 9 | 2 | 0 | 0 | 2 | 4 | 4.42 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 48 | 0 | 2 | 3 | 2.82 | .257 | 0.99 | 5.0 | 4.1 | 8.6 | 60.2 | 33 | 19 | 19 | 4 | 27 | 57 | 0 | 11 | 2 | 0 | 0 | 3 | 3 | 3.47 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 32 | 0 | 3 | 4 | 3.97 | .306 | 1.26 | 7.9 | 3.4 | 9.5 | 34.0 | 30 | 15 | 15 | 4 | 13 | 36 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 3.74 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 38 | 0 | 3 | 2 | 3.32 | .283 | 1.18 | 6.9 | 3.8 | 10.7 | 38.0 | 29 | 14 | 14 | 2 | 16 | 45 | 0 | 4 | 0 | 0 | 0 | 0 | 2 | 2.58 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 53 | 25 | 0 | 5 | 0 | 4.51 | .319 | 1.40 | 9.1 | 3.6 | 7.9 | 103.2 | 104 | 52 | 52 | 17 | 41 | 90 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 4.62 |