| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 29 | 29 | 10 | 12 | 4.01 | .281 | 1.15 | 8.5 | 1.9 | 9.4 | 204.1 | 192 | 94 | 91 | 24 | 43 | 212 | 6 | 0 | 0 | 0 | 16 | 4 | 5 | 3.14 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 77 | 27 | 27 | 12 | 9 | 6.08 | .341 | 1.53 | 10.2 | 3.5 | 9.3 | 160.0 | 182 | 108 | 108 | 30 | 62 | 166 | 2 | 0 | 0 | 0 | 9 | 4 | 2 | 4.60 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 24 | 2005 | R | 71 | 26 | 25 | 15 | 5 | 4.63 | .309 | 1.31 | 8.5 | 3.3 | 7.1 | 165.1 | 156 | 87 | 85 | 23 | 61 | 131 | 0 | 0 | 0 | 0 | 11 | 5 | 5 | 4.42 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 29 | 27 | 13 | 9 | 5.62 | .347 | 1.56 | 11.2 | 2.8 | 7.1 | 169.2 | 211 | 109 | 106 | 33 | 53 | 134 | 2 | 0 | 0 | 0 | 13 | 7 | 4 | 5.02 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 74 | 0 | 5 | 1 | 3.26 | .300 | 1.26 | 8.0 | 3.4 | 8.0 | 85.2 | 76 | 32 | 31 | 8 | 32 | 76 | 0 | 2 | 0 | 0 | 0 | 2 | 3 | 3.64 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 49 | 0 | 6 | 2 | 2.37 | .260 | 1.04 | 6.8 | 2.7 | 7.8 | 60.2 | 45 | 16 | 16 | 4 | 18 | 52 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.08 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 48 | 47 | 0 | 2 | 0 | 5.51 | .345 | 1.56 | 10.4 | 3.8 | 7.0 | 50.2 | 58 | 32 | 31 | 12 | 21 | 39 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.88 |
| SU | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 48 | 0 | 1 | 1 | 3.74 | .274 | 1.09 | 6.6 | 3.2 | 9.5 | 53.0 | 39 | 22 | 22 | 6 | 19 | 56 | 0 | 2 | 4 | 0 | 0 | 2 | 2 | 3.55 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 55 | 0 | 6 | 4 | 1.65 | .289 | 1.18 | 7.2 | 3.5 | 8.1 | 60.0 | 48 | 12 | 11 | 1 | 23 | 54 | 0 | 28 | 1 | 0 | 0 | 2 | 1 | 2.67 |