| SP | Blyleven, B.Blyleven, Bert + >> | 0 | 1977 | R | 80 | 32 | 32 | 15 | 10 | 3.55 | .273 | 1.07 | 6.6 | 3.0 | 6.0 | 225.1 | 165 | 96 | 89 | 20 | 76 | 151 | 8 | 0 | 0 | 1 | 19 | 13 | 7 | 4.00 |
| SP | Santana, J.Santana, Johan + >> | 0 | 2004 | L | 94 | 33 | 33 | 14 | 9 | 3.91 | .289 | 1.14 | 7.6 | 2.7 | 9.0 | 207.1 | 175 | 95 | 90 | 22 | 62 | 206 | 5 | 0 | 0 | 2 | 19 | 16 | 9 | 3.52 |
| SP | Newhouser, H.Newhouser, Hal $ >> | 0 | 1946 | L | 73 | 31 | 31 | 12 | 12 | 3.28 | .279 | 1.14 | 7.8 | 2.5 | 6.4 | 228.0 | 197 | 86 | 83 | 21 | 63 | 163 | 9 | 0 | 0 | 2 | 18 | 5 | 4 | 3.66 |
| RP | Nathan, J.Nathan, Joe † + >> | 0 | 2006 | R | 96 | 79 | 0 | 12 | 4 | 1.79 | .206 | 0.78 | 4.8 | 2.2 | 9.6 | 125.2 | 67 | 26 | 25 | 6 | 31 | 133 | 0 | 15 | 1 | 0 | 0 | 0 | 0 | 2.24 |
| RP | Bastardo, A.Bastardo, Antonio >> | 0 | 2011 | L | 83 | 91 | 0 | 3 | 2 | 2.75 | .268 | 1.06 | 5.6 | 4.1 | 9.3 | 55.2 | 34 | 17 | 17 | 5 | 25 | 57 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 3.58 |
| RP | Worrell, T.Worrell, Todd >> | 0 | 1995 | R | 50 | 16 | 0 | 1 | 1 | 2.21 | .176 | 0.64 | 3.6 | 2.3 | 5.0 | 20.1 | 8 | 5 | 5 | 2 | 5 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.95 |
| SP | Liriano, F.Liriano, Francisco # >> | 0 | 2006 | L | 78 | 32 | 32 | 6 | 6 | 4.79 | .292 | 1.23 | 8.0 | 3.2 | 8.3 | 120.1 | 106 | 66 | 64 | 15 | 42 | 111 | 0 | 0 | 0 | 0 | 2 | 1 | 5 | 3.85 |
| SP | Driscoll, D.Driscoll, Denny >> | 0 | 1883 | L | 59 | 12 | 1 | 1 | 0 | 2.66 | .211 | 0.74 | 5.7 | 1.0 | 3.4 | 47.1 | 30 | 14 | 14 | 4 | 5 | 18 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.85 |