| SP | Carrasco, C.Carrasco, Carlos >> | 28 | 2015 | R | 92 | 29 | 29 | 8 | 12 | 4.27 | .319 | 1.38 | 8.6 | 3.9 | 10.1 | 168.2 | 160 | 85 | 80 | 12 | 72 | 189 | 1 | 0 | 0 | 0 | 16 | 5 | 10 | 3.05 |
| SP | Estrada, M.Estrada, Marco >> | 32 | 2015 | R | 90 | 29 | 29 | 11 | 13 | 3.93 | .309 | 1.29 | 8.2 | 3.4 | 7.0 | 151.0 | 138 | 70 | 66 | 18 | 57 | 118 | 0 | 0 | 0 | 0 | 9 | 8 | 0 | 4.28 |
| SP | Lester, J.Lester, Jon # >> | 31 | 2015 | L | 83 | 28 | 28 | 12 | 3 | 3.41 | .296 | 1.25 | 9.4 | 1.9 | 9.3 | 176.2 | 183 | 70 | 67 | 14 | 38 | 181 | 0 | 0 | 0 | 0 | 19 | 2 | 2 | 2.66 |
| SP | Hendricks, K.Hendricks, Kyle >> | 25 | 2015 | R | 72 | 28 | 28 | 12 | 10 | 3.54 | .299 | 1.26 | 8.1 | 3.3 | 7.0 | 160.0 | 144 | 74 | 63 | 11 | 58 | 124 | 0 | 0 | 0 | 0 | 17 | 3 | 6 | 3.49 |
| SP | Leake, M.Leake, Mike # >> | 27 | 2015 | R | 67 | 30 | 28 | 13 | 8 | 4.49 | .331 | 1.45 | 9.9 | 3.2 | 6.2 | 170.1 | 187 | 93 | 85 | 18 | 60 | 117 | 2 | 0 | 0 | 1 | 16 | 6 | 6 | 4.16 |
| CL | Ramos, A.Ramos, A.J. † >> | 28 | 2015 | R | 88 | 64 | 0 | 5 | 6 | 4.19 | .288 | 1.19 | 7.2 | 3.5 | 10.8 | 66.2 | 53 | 31 | 31 | 3 | 26 | 79 | 0 | 31 | 4 | 0 | 0 | 2 | 1 | 2.47 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 87 | 90 | 0 | 7 | 1 | 4.24 | .313 | 1.35 | 8.6 | 3.6 | 10.0 | 91.1 | 87 | 46 | 43 | 11 | 36 | 101 | 0 | 2 | 3 | 0 | 0 | 2 | 2 | 3.60 |
| RP | Siegrist, K.Siegrist, Kevin >> | 25 | 2015 | L | 70 | 74 | 0 | 3 | 0 | 3.38 | .320 | 1.29 | 6.8 | 4.8 | 10.0 | 56.0 | 42 | 21 | 21 | 1 | 30 | 62 | 0 | 1 | 1 | 0 | 0 | 7 | 0 | 3.00 |
| RP | Grilli, J.Grilli, Jason >> | 39 | 2015 | R | 63 | 76 | 0 | 1 | 4 | 3.98 | .309 | 1.33 | 8.0 | 4.0 | 9.6 | 72.1 | 64 | 32 | 32 | 5 | 32 | 77 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.14 |
| RP | Salas, F.Salas, Fernando >> | 30 | 2015 | R | 48 | 53 | 0 | 1 | 4 | 3.97 | .339 | 1.50 | 10.4 | 3.2 | 8.8 | 56.2 | 65 | 28 | 25 | 5 | 20 | 55 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 3.38 |