| SP | Keuchel, D.Keuchel, Dallas † # >> | 27 | 2015 | L | 94 | 29 | 29 | 14 | 11 | 3.93 | .289 | 1.18 | 8.6 | 2.0 | 7.6 | 217.2 | 208 | 97 | 95 | 23 | 49 | 184 | 7 | 0 | 0 | 3 | 14 | 9 | 3 | 3.48 |
| SP | Kazmir, S.Kazmir, Scott >> | 31 | 2015 | L | 70 | 28 | 28 | 4 | 17 | 4.76 | .335 | 1.49 | 9.7 | 3.7 | 7.1 | 164.2 | 177 | 90 | 87 | 18 | 68 | 130 | 0 | 0 | 0 | 0 | 10 | 4 | 5 | 4.16 |
| SP | Walker, T.Walker, Taijuan # >> | 22 | 2015 | R | 65 | 28 | 28 | 10 | 13 | 5.33 | .321 | 1.40 | 10.5 | 2.1 | 6.9 | 165.1 | 192 | 98 | 98 | 27 | 39 | 126 | 1 | 0 | 0 | 0 | 11 | 3 | 3 | 4.36 |
| SP | Zimmermann, J.Zimmermann, Jordan >> | 29 | 2015 | R | 57 | 28 | 28 | 6 | 16 | 5.44 | .347 | 1.59 | 11.5 | 2.9 | 7.3 | 168.2 | 214 | 103 | 102 | 25 | 54 | 137 | 0 | 0 | 0 | 0 | 14 | 1 | 0 | 4.29 |
| SP | Martinez, C.Martinez, Carlos >> | 24 | 2015 | R | 56 | 28 | 28 | 5 | 6 | 4.37 | .314 | 1.34 | 9.3 | 2.8 | 9.2 | 173.0 | 178 | 94 | 84 | 14 | 53 | 177 | 0 | 0 | 0 | 0 | 14 | 7 | 7 | 3.05 |
| RP | Robertson, D.Robertson, David >> | 30 | 2015 | R | 92 | 75 | 0 | 5 | 1 | 1.88 | .267 | 1.08 | 6.6 | 3.2 | 11.2 | 100.2 | 73 | 24 | 21 | 2 | 36 | 124 | 0 | 6 | 1 | 0 | 0 | 1 | 6 | 1.89 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 35 | 2015 | R | 67 | 70 | 0 | 2 | 7 | 4.26 | .318 | 1.40 | 9.4 | 3.3 | 7.7 | 88.2 | 92 | 44 | 42 | 11 | 32 | 75 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 4.01 |
| RP | Warren, A.Warren, Adam >> | 27 | 2015 | R | 47 | 56 | 0 | 7 | 9 | 3.39 | .315 | 1.38 | 8.7 | 3.8 | 6.8 | 95.2 | 92 | 39 | 36 | 11 | 40 | 72 | 0 | 6 | 7 | 0 | 0 | 0 | 2 | 4.25 |
| RP | Holland, G.Holland, Greg >> | 29 | 2015 | R | 23 | 23 | 0 | 0 | 1 | 6.67 | .380 | 1.84 | 10.0 | 6.8 | 9.3 | 28.1 | 31 | 21 | 21 | 2 | 21 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 4.11 |
| SP | McHugh, C.McHugh, Collin >> | 28 | 2015 | R | 45 | 10 | 0 | 0 | 2 | 6.60 | .308 | 1.33 | 10.8 | 1.2 | 10.2 | 15.0 | 18 | 11 | 11 | 3 | 2 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.73 |