| SP | Scherzer, M.Scherzer, Max >> | 31 | 2015 | R | 99 | 23 | 23 | 8 | 9 | 3.18 | .262 | 1.05 | 7.7 | 1.7 | 10.2 | 170.0 | 146 | 61 | 60 | 15 | 32 | 193 | 2 | 0 | 0 | 0 | 16 | 3 | 2 | 2.49 |
| SP | Garcia, J.Garcia, Jaime † >> | 29 | 2015 | L | 88 | 22 | 22 | 14 | 4 | 2.67 | .283 | 1.17 | 7.7 | 2.9 | 7.3 | 151.2 | 129 | 48 | 45 | 6 | 48 | 122 | 3 | 0 | 0 | 1 | 18 | 3 | 8 | 2.91 |
| SP | Cueto, J.Cueto, Johnny # >> | 29 | 2015 | R | 74 | 22 | 22 | 7 | 6 | 5.40 | .312 | 1.33 | 9.8 | 2.2 | 7.3 | 123.1 | 134 | 74 | 74 | 18 | 30 | 100 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 4.11 |
| RP | Smith, C.Smith, Carson >> | 25 | 2015 | R | 87 | 69 | 0 | 1 | 2 | 4.37 | .295 | 1.24 | 9.2 | 2.1 | 8.0 | 55.2 | 56 | 29 | 27 | 5 | 13 | 49 | 0 | 1 | 2 | 0 | 0 | 1 | 4 | 3.16 |
| RP | Chapman, A.Chapman, Aroldis >> | 27 | 2015 | L | 78 | 55 | 0 | 3 | 2 | 2.52 | .257 | 1.04 | 6.2 | 3.3 | 10.5 | 35.2 | 24 | 10 | 10 | 1 | 13 | 41 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 2.14 |
| RP | Melancon, M.Melancon, Mark >> | 30 | 2015 | R | 85 | 57 | 0 | 4 | 1 | 2.62 | .260 | 1.05 | 8.0 | 1.6 | 9.6 | 44.2 | 39 | 13 | 13 | 7 | 8 | 47 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.48 |
| RP | Rondon, H.Rondon, Hector >> | 27 | 2015 | R | 75 | 38 | 0 | 2 | 2 | 3.28 | .339 | 1.50 | 12.0 | 1.9 | 6.8 | 24.2 | 32 | 10 | 9 | 3 | 5 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.88 |
| RP | Narveson, C.Narveson, Chris >> | 34 | 2015 | L | 71 | 25 | 0 | 2 | 2 | 2.52 | .312 | 1.32 | 6.5 | 5.4 | 9.4 | 25.0 | 18 | 7 | 7 | 1 | 15 | 26 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.36 |
| RP | Wilson, J.Wilson, Justin >> | 27 | 2015 | L | 67 | 26 | 0 | 3 | 0 | 2.78 | .284 | 1.19 | 8.6 | 2.5 | 10.2 | 22.2 | 21 | 8 | 7 | 0 | 6 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1.55 |