| SP | deGrom, J.deGrom, Jacob >> | 27 | 2015 | R | 97 | 29 | 29 | 9 | 11 | 4.15 | .329 | 1.43 | 10.1 | 2.8 | 8.6 | 173.1 | 195 | 80 | 80 | 16 | 53 | 165 | 1 | 0 | 0 | 1 | 17 | 7 | 4 | 3.34 |
| SP | Verlander, J.Verlander, Justin # >> | 32 | 2015 | R | 84 | 29 | 29 | 13 | 9 | 5.16 | .325 | 1.39 | 9.5 | 3.1 | 7.0 | 165.2 | 174 | 100 | 95 | 22 | 56 | 129 | 1 | 0 | 0 | 0 | 14 | 9 | 2 | 4.35 |
| SP | Garcia, J.Garcia, Jaime >> | 29 | 2015 | L | 88 | 28 | 28 | 14 | 9 | 3.37 | .291 | 1.22 | 8.1 | 2.9 | 6.6 | 176.1 | 159 | 66 | 66 | 13 | 56 | 130 | 2 | 0 | 0 | 2 | 19 | 2 | 3 | 3.47 |
| SP | Peavy, J.Peavy, Jake # >> | 34 | 2015 | R | 74 | 29 | 28 | 8 | 11 | 5.24 | .351 | 1.57 | 11.4 | 2.8 | 7.1 | 144.1 | 182 | 85 | 84 | 14 | 44 | 113 | 0 | 0 | 0 | 0 | 10 | 8 | 3 | 3.78 |
| SP | Buchholz, C.Buchholz, Clay >> | 31 | 2015 | R | 60 | 27 | 27 | 8 | 10 | 4.40 | .309 | 1.30 | 9.4 | 2.3 | 8.1 | 147.1 | 154 | 75 | 72 | 16 | 38 | 132 | 0 | 0 | 0 | 0 | 15 | 6 | 3 | 3.52 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 27 | 2015 | R | 86 | 78 | 0 | 4 | 2 | 3.84 | .326 | 1.43 | 7.4 | 5.4 | 10.5 | 96.0 | 79 | 44 | 41 | 8 | 58 | 112 | 0 | 2 | 3 | 0 | 0 | 2 | 2 | 3.63 |
| RP | Clippard, T.Clippard, Tyler >> | 30 | 2015 | R | 73 | 73 | 0 | 3 | 3 | 2.44 | .269 | 1.09 | 6.7 | 3.2 | 7.7 | 92.1 | 68 | 30 | 25 | 5 | 33 | 79 | 0 | 1 | 3 | 0 | 0 | 1 | 8 | 3.10 |
| RP | Herrera, K.Herrera, Kelvin >> | 25 | 2015 | R | 68 | 59 | 0 | 6 | 2 | 2.56 | .304 | 1.28 | 7.0 | 4.6 | 7.6 | 63.1 | 49 | 22 | 18 | 1 | 32 | 53 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.14 |
| CL | Rodriguez, F.Rodriguez, Francisco † >> | 33 | 2015 | R | 98 | 69 | 0 | 5 | 6 | 3.35 | .286 | 1.20 | 7.8 | 3.2 | 9.3 | 80.2 | 69 | 31 | 30 | 11 | 28 | 83 | 0 | 27 | 2 | 0 | 0 | 0 | 3 | 3.76 |