| SP | Scherzer, M.Scherzer, Max >> | 31 | 2015 | R | 99 | 37 | 37 | 19 | 12 | 3.87 | .290 | 1.21 | 8.8 | 2.0 | 10.2 | 242.0 | 237 | 110 | 104 | 28 | 55 | 275 | 0 | 0 | 0 | 0 | 22 | 4 | 10 | 2.96 |
| SP | Cole, G.Cole, Gerrit † >> | 24 | 2015 | R | 84 | 37 | 37 | 11 | 16 | 4.63 | .319 | 1.39 | 10.0 | 2.5 | 8.5 | 229.1 | 255 | 125 | 118 | 30 | 64 | 217 | 1 | 0 | 0 | 0 | 20 | 4 | 2 | 3.70 |
| SP | Iwakuma, H.Iwakuma, Hisashi # >> | 34 | 2015 | R | 81 | 36 | 36 | 17 | 13 | 3.93 | .296 | 1.22 | 8.8 | 2.2 | 7.7 | 243.0 | 237 | 113 | 106 | 34 | 59 | 208 | 5 | 0 | 0 | 2 | 18 | 10 | 3 | 3.96 |
| SP | Dickey, R.Dickey, R.A. >> | 41 | 2015 | R | 62 | 30 | 29 | 9 | 7 | 4.45 | .321 | 1.40 | 9.0 | 3.5 | 6.8 | 184.0 | 185 | 98 | 91 | 23 | 72 | 140 | 0 | 0 | 0 | 0 | 14 | 4 | 11 | 4.34 |
| SU | Uehara, K.Uehara, Koji # >> | 40 | 2015 | R | 95 | 82 | 0 | 5 | 1 | 4.28 | .280 | 1.15 | 7.8 | 2.7 | 9.6 | 88.1 | 76 | 42 | 42 | 7 | 26 | 94 | 0 | 2 | 4 | 0 | 0 | 1 | 4 | 2.82 |
| CL | Chapman, A.Chapman, Aroldis † >> | 27 | 2015 | L | 78 | 87 | 0 | 7 | 8 | 4.43 | .332 | 1.46 | 9.1 | 4.1 | 11.1 | 83.1 | 84 | 44 | 41 | 10 | 38 | 102 | 0 | 42 | 7 | 0 | 0 | 2 | 5 | 3.55 |
| RP | Garcia, Y.Garcia, Yimi >> | 24 | 2015 | R | 84 | 89 | 0 | 5 | 3 | 2.60 | .288 | 1.19 | 8.9 | 1.9 | 9.7 | 86.2 | 85 | 29 | 25 | 11 | 18 | 93 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 3.20 |
| RP | Jepsen, K.Jepsen, Kevin >> | 31 | 2015 | R | 66 | 76 | 0 | 4 | 6 | 3.19 | .325 | 1.43 | 8.5 | 4.4 | 7.5 | 73.1 | 69 | 31 | 26 | 8 | 36 | 61 | 0 | 6 | 1 | 0 | 0 | 1 | 1 | 4.27 |