| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 100 | 30 | 30 | 19 | 7 | 2.82 | .273 | 1.10 | 7.3 | 2.6 | 8.8 | 220.1 | 179 | 75 | 69 | 13 | 63 | 215 | 5 | 0 | 0 | 3 | 23 | 6 | 4 | 2.75 |
| SP | Price, D.Price, David † >> | 30 | 2015 | L | 90 | 29 | 29 | 14 | 5 | 3.82 | .299 | 1.26 | 8.5 | 2.8 | 9.6 | 198.0 | 188 | 86 | 84 | 21 | 61 | 211 | 3 | 0 | 0 | 1 | 15 | 4 | 1 | 3.23 |
| SP | Strasburg, S.Strasburg, Stephen >> | 26 | 2015 | R | 82 | 28 | 28 | 8 | 7 | 4.81 | .331 | 1.44 | 10.1 | 3.0 | 8.5 | 149.2 | 167 | 81 | 80 | 17 | 49 | 141 | 0 | 0 | 0 | 0 | 9 | 6 | 4 | 3.70 |
| SP | Fernandez, J.Fernandez, Jose † >> | 23 | 2015 | R | 71 | 28 | 28 | 14 | 6 | 3.04 | .299 | 1.25 | 8.7 | 2.6 | 9.5 | 171.2 | 165 | 62 | 58 | 16 | 50 | 181 | 0 | 0 | 0 | 0 | 17 | 5 | 7 | 3.06 |
| RP | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 100 | 83 | 0 | 10 | 6 | 3.35 | .259 | 1.03 | 6.9 | 2.4 | 10.1 | 115.2 | 88 | 44 | 43 | 13 | 31 | 129 | 0 | 11 | 4 | 0 | 0 | 2 | 2 | 3.09 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 82 | 71 | 0 | 6 | 3 | 3.10 | .275 | 1.13 | 7.5 | 2.7 | 8.1 | 93.0 | 77 | 37 | 32 | 7 | 28 | 84 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 3.11 |
| RP | Madson, R.Madson, Ryan >> | 35 | 2015 | R | 78 | 65 | 0 | 4 | 4 | 2.91 | .271 | 1.10 | 7.5 | 2.4 | 6.7 | 74.1 | 62 | 25 | 24 | 9 | 20 | 55 | 0 | 10 | 4 | 0 | 0 | 1 | 0 | 3.95 |
| RP | Street, H.Street, Huston >> | 32 | 2015 | R | 53 | 27 | 0 | 1 | 1 | 5.10 | .308 | 1.33 | 6.3 | 5.7 | 6.6 | 30.0 | 21 | 17 | 17 | 3 | 19 | 22 | 0 | 2 | 1 | 0 | 0 | 0 | 5 | 4.73 |