| SP | Greinke, Z.Greinke, Zack † # >> | 32 | 2015 | R | 98 | 35 | 35 | 18 | 9 | 3.09 | .265 | 1.06 | 7.7 | 1.8 | 8.2 | 265.0 | 227 | 92 | 91 | 26 | 54 | 242 | 9 | 0 | 0 | 5 | 23 | 5 | 5 | 3.12 |
| SP | Salazar, D.Salazar, Danny >> | 25 | 2015 | R | 87 | 34 | 34 | 13 | 5 | 4.77 | .333 | 1.48 | 9.4 | 3.9 | 10.7 | 168.0 | 175 | 91 | 89 | 27 | 73 | 200 | 0 | 0 | 0 | 0 | 9 | 4 | 1 | 4.08 |
| SP | Liriano, F.Liriano, Francisco >> | 32 | 2015 | L | 79 | 33 | 33 | 15 | 5 | 4.13 | .331 | 1.47 | 9.5 | 3.7 | 9.8 | 200.1 | 211 | 94 | 92 | 23 | 83 | 217 | 0 | 0 | 0 | 0 | 16 | 4 | 7 | 3.63 |
| SP | Cueto, J.Cueto, Johnny >> | 29 | 2015 | R | 74 | 34 | 33 | 15 | 11 | 4.54 | .315 | 1.35 | 9.8 | 2.3 | 6.7 | 220.0 | 240 | 119 | 111 | 28 | 56 | 163 | 4 | 0 | 1 | 3 | 15 | 7 | 0 | 4.03 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 33 | 2015 | R | 98 | 89 | 0 | 8 | 4 | 2.82 | .290 | 1.20 | 8.4 | 2.5 | 9.2 | 124.2 | 116 | 41 | 39 | 13 | 34 | 127 | 0 | 9 | 8 | 0 | 0 | 3 | 3 | 3.21 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 82 | 63 | 0 | 8 | 3 | 3.24 | .275 | 1.12 | 7.0 | 3.0 | 7.4 | 86.0 | 67 | 32 | 31 | 8 | 29 | 71 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 3.64 |
| RP | Watson, T.Watson, Tony † >> | 30 | 2015 | L | 81 | 77 | 0 | 9 | 5 | 2.49 | .253 | 0.99 | 7.3 | 1.6 | 6.9 | 101.1 | 82 | 29 | 28 | 8 | 18 | 77 | 0 | 14 | 4 | 0 | 0 | 3 | 2 | 3.13 |
| RP | Narveson, C.Narveson, Chris † >> | 34 | 2015 | L | 71 | 62 | 0 | 7 | 4 | 2.92 | .306 | 1.30 | 8.7 | 3.0 | 10.0 | 89.1 | 86 | 31 | 29 | 7 | 30 | 99 | 0 | 20 | 4 | 0 | 0 | 2 | 0 | 2.88 |
| RP | Siegrist, K.Siegrist, Kevin >> | 25 | 2015 | L | 70 | 13 | 0 | 2 | 1 | 5.40 | .308 | 1.33 | 9.0 | 3.0 | 8.4 | 15.0 | 15 | 9 | 9 | 3 | 5 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.73 |
| RP | Grilli, J.Grilli, Jason >> | 39 | 2015 | R | 63 | 27 | 0 | 3 | 2 | 7.66 | .393 | 1.86 | 12.0 | 5.3 | 10.5 | 24.2 | 32 | 21 | 21 | 6 | 14 | 28 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 5.92 |
| RP | Blanton, J.Blanton, Joe >> | 35 | 2015 | R | 57 | 35 | 0 | 2 | 1 | 4.95 | .340 | 1.51 | 10.8 | 2.9 | 9.0 | 56.1 | 67 | 32 | 31 | 10 | 18 | 56 | 0 | 0 | 3 | 0 | 0 | 2 | 1 | 4.39 |