| SP | Richard, J.Richard, J.R. # >> | 30 | 1980 | R | 90 | 21 | 21 | 9 | 7 | 3.63 | .290 | 1.22 | 7.4 | 3.5 | 7.4 | 139.0 | 115 | 57 | 56 | 15 | 54 | 115 | 0 | 0 | 0 | 0 | 12 | 1 | 1 | 3.94 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 20 | 20 | 10 | 6 | 3.25 | .261 | 1.05 | 6.6 | 2.9 | 7.5 | 135.2 | 99 | 49 | 49 | 13 | 43 | 113 | 3 | 0 | 0 | 1 | 14 | 2 | 1 | 3.58 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 20 | 20 | 9 | 7 | 4.37 | .291 | 1.20 | 6.8 | 4.1 | 3.7 | 123.2 | 93 | 60 | 60 | 17 | 56 | 50 | 1 | 0 | 0 | 0 | 11 | 3 | 5 | 5.42 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 20 | 19 | 6 | 4 | 4.74 | .315 | 1.36 | 9.4 | 2.9 | 5.4 | 123.1 | 128 | 71 | 65 | 19 | 40 | 74 | 3 | 0 | 0 | 0 | 9 | 2 | 5 | 4.83 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 50 | 0 | 5 | 1 | 2.02 | .260 | 1.03 | 5.3 | 4.0 | 7.9 | 58.0 | 34 | 15 | 13 | 5 | 26 | 51 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 3.76 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 34 | 0 | 1 | 3 | 2.95 | .293 | 1.20 | 6.2 | 4.7 | 4.5 | 42.2 | 29 | 18 | 14 | 5 | 22 | 21 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.26 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 28 | 0 | 3 | 1 | 3.16 | .304 | 1.28 | 9.0 | 2.6 | 9.3 | 31.1 | 31 | 11 | 11 | 4 | 9 | 32 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3.58 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 47 | 0 | 2 | 4 | 1.95 | .265 | 1.07 | 5.6 | 4.1 | 9.8 | 55.1 | 34 | 16 | 12 | 4 | 25 | 60 | 0 | 24 | 3 | 0 | 0 | 1 | 5 | 3.18 |