| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 29 | 29 | 11 | 14 | 4.45 | .289 | 1.20 | 8.9 | 1.9 | 8.3 | 218.1 | 216 | 110 | 108 | 27 | 47 | 202 | 5 | 0 | 0 | 0 | 10 | 3 | 4 | 3.44 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 29 | 29 | 7 | 17 | 5.71 | .338 | 1.48 | 9.8 | 3.6 | 3.9 | 176.2 | 191 | 118 | 112 | 19 | 71 | 77 | 1 | 0 | 0 | 0 | 12 | 9 | 8 | 4.89 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 29 | 29 | 10 | 16 | 4.41 | .334 | 1.47 | 10.0 | 3.3 | 6.3 | 210.1 | 234 | 116 | 103 | 26 | 76 | 148 | 8 | 0 | 0 | 0 | 11 | 6 | 8 | 4.37 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 74 | 0 | 6 | 3 | 3.59 | .281 | 1.17 | 7.0 | 3.6 | 8.4 | 90.1 | 70 | 39 | 36 | 6 | 36 | 84 | 0 | 6 | 3 | 0 | 0 | 0 | 4 | 3.20 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 62 | 0 | 3 | 3 | 4.82 | .371 | 1.71 | 9.0 | 6.4 | 8.7 | 56.0 | 56 | 32 | 30 | 5 | 40 | 54 | 0 | 6 | 2 | 0 | 0 | 3 | 3 | 4.54 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 42 | 0 | 1 | 1 | 3.35 | .294 | 1.23 | 7.1 | 4.1 | 8.0 | 53.2 | 42 | 23 | 20 | 2 | 24 | 47 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.13 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 54 | 1 | 1 | 0 | 1 | 27.00 | .583 | 4.20 | 54.0 | 9.0 | 0.0 | 1.2 | 6 | 5 | 5 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.00 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 2 | 0 | 0 | 0 | 2.08 | .278 | 1.15 | 11.3 | 0.0 | 4.5 | 4.1 | 5 | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.25 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 26 | 0 | 2 | 4 | 4.38 | .353 | 1.64 | 9.7 | 5.1 | 5.5 | 51.1 | 55 | 25 | 25 | 7 | 29 | 31 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.27 |