| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 34 | 34 | 12 | 16 | 3.38 | .276 | 1.13 | 7.3 | 2.9 | 8.4 | 269.0 | 217 | 105 | 101 | 29 | 87 | 251 | 10 | 0 | 0 | 3 | 18 | 4 | 5 | 3.55 |
| SP | Brown, M.Brown, Mordecai † # >> | 32 | 1908 | R | 85 | 33 | 33 | 16 | 8 | 3.89 | .267 | 1.09 | 8.3 | 1.5 | 4.4 | 254.2 | 235 | 115 | 110 | 30 | 43 | 125 | 11 | 0 | 0 | 4 | 17 | 1 | 5 | 4.07 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 32 | 32 | 8 | 15 | 5.31 | .337 | 1.50 | 10.5 | 3.0 | 7.7 | 210.0 | 245 | 126 | 124 | 24 | 71 | 180 | 3 | 0 | 0 | 1 | 13 | 4 | 3 | 3.84 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 31 | 31 | 7 | 17 | 5.94 | .332 | 1.45 | 8.8 | 4.3 | 6.1 | 189.1 | 184 | 128 | 125 | 35 | 90 | 128 | 0 | 0 | 0 | 0 | 11 | 8 | 8 | 5.61 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 31 | 31 | 3 | 12 | 5.87 | .344 | 1.54 | 10.5 | 3.4 | 8.7 | 130.1 | 152 | 91 | 85 | 20 | 49 | 126 | 0 | 0 | 0 | 0 | 1 | 4 | 3 | 4.28 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 79 | 0 | 6 | 9 | 3.74 | .281 | 1.16 | 7.3 | 3.2 | 9.3 | 108.1 | 88 | 45 | 45 | 16 | 38 | 112 | 0 | 7 | 7 | 0 | 0 | 1 | 0 | 3.94 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 60 | 0 | 2 | 0 | 4.23 | .322 | 1.41 | 9.0 | 3.8 | 7.4 | 78.2 | 78 | 37 | 37 | 14 | 33 | 64 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 5.00 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 54 | 0 | 1 | 6 | 7.41 | .361 | 1.68 | 10.9 | 4.3 | 8.5 | 58.1 | 70 | 50 | 48 | 14 | 28 | 55 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 5.74 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 35 | 0 | 4 | 3 | 6.19 | .333 | 1.50 | 10.3 | 3.2 | 5.4 | 48.0 | 55 | 35 | 33 | 9 | 17 | 29 | 0 | 6 | 3 | 0 | 0 | 0 | 2 | 5.29 |