| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 93 | 30 | 30 | 13 | 10 | 3.72 | .281 | 1.13 | 7.9 | 2.3 | 5.4 | 213.0 | 186 | 88 | 88 | 15 | 55 | 127 | 11 | 0 | 0 | 2 | 16 | 9 | 2 | 3.62 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 28 | 28 | 10 | 10 | 3.86 | .291 | 1.19 | 8.7 | 2.0 | 4.6 | 189.0 | 183 | 87 | 81 | 24 | 42 | 96 | 4 | 0 | 0 | 1 | 18 | 8 | 3 | 4.43 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 29 | 29 | 11 | 8 | 3.84 | .291 | 1.22 | 8.2 | 2.7 | 5.1 | 203.2 | 186 | 91 | 87 | 13 | 62 | 116 | 3 | 0 | 0 | 1 | 17 | 3 | 4 | 3.65 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 55 | 0 | 7 | 7 | 3.25 | .285 | 1.18 | 6.9 | 3.9 | 7.9 | 63.2 | 48 | 25 | 23 | 8 | 27 | 55 | 0 | 27 | 6 | 0 | 0 | 1 | 0 | 4.24 |
| RP | Clippard, T.Clippard, Tyler # >> | 26 | 2011 | R | 79 | 51 | 0 | 4 | 3 | 4.33 | .316 | 1.37 | 8.3 | 4.0 | 8.7 | 52.0 | 48 | 25 | 25 | 6 | 23 | 50 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 3.96 |
| SU | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 36 | 0 | 5 | 1 | 2.27 | .274 | 1.13 | 4.6 | 5.8 | 8.3 | 39.2 | 20 | 10 | 10 | 3 | 25 | 36 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.08 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 31 | 0 | 1 | 2 | 4.09 | .336 | 1.48 | 9.3 | 4.1 | 5.7 | 33.0 | 34 | 16 | 15 | 4 | 15 | 21 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 4.76 |
| RP | Charlton, N.Charlton, Norm >> | 30 | 1993 | L | 31 | 10 | 0 | 0 | 1 | 1.80 | .362 | 1.60 | 9.0 | 5.4 | 9.0 | 10.0 | 10 | 3 | 2 | 0 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.10 |
| RP | Hoffman, T.Hoffman, Trevor # >> | 31 | 1998 | R | 75 | 28 | 0 | 3 | 1 | 5.59 | .326 | 1.34 | 8.1 | 4.0 | 8.4 | 29.0 | 26 | 18 | 18 | 5 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 5.03 |
| RP | Saito, T.Saito, Takashi # >> | 37 | 2007 | R | 91 | 42 | 0 | 1 | 2 | 5.02 | .295 | 1.21 | 7.5 | 3.3 | 8.8 | 43.0 | 36 | 25 | 24 | 6 | 16 | 42 | 0 | 6 | 7 | 0 | 0 | 2 | 0 | 4.12 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 66 | 9 | 1 | 2 | 2 | 6.20 | .299 | 1.28 | 8.8 | 2.9 | 5.0 | 40.2 | 39 | 28 | 28 | 6 | 13 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.83 |