| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 21 | 21 | 11 | 8 | 4.21 | .326 | 1.41 | 9.4 | 3.4 | 8.9 | 134.2 | 140 | 67 | 63 | 13 | 50 | 133 | 1 | 0 | 0 | 0 | 13 | 5 | 3 | 3.51 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 21 | 21 | 5 | 9 | 5.43 | .348 | 1.53 | 10.5 | 3.3 | 9.3 | 126.0 | 147 | 81 | 76 | 18 | 46 | 130 | 0 | 0 | 0 | 0 | 10 | 9 | 1 | 4.10 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 20 | 20 | 8 | 6 | 4.62 | .341 | 1.54 | 9.9 | 4.1 | 8.1 | 126.2 | 138 | 73 | 65 | 15 | 57 | 113 | 0 | 0 | 0 | 0 | 11 | 2 | 5 | 4.16 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 20 | 20 | 10 | 8 | 3.13 | .254 | 1.00 | 7.3 | 1.7 | 5.0 | 146.2 | 119 | 53 | 51 | 16 | 28 | 81 | 5 | 0 | 0 | 1 | 14 | 3 | 0 | 3.95 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 20 | 20 | 9 | 4 | 4.82 | .322 | 1.39 | 7.3 | 5.2 | 6.9 | 127.0 | 103 | 68 | 68 | 13 | 74 | 98 | 1 | 0 | 0 | 1 | 10 | 4 | 10 | 4.63 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 26 | 0 | 1 | 2 | 2.22 | .286 | 1.20 | 7.1 | 3.9 | 5.1 | 28.1 | 22 | 9 | 7 | 2 | 12 | 16 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.07 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 13 | 0 | 2 | 0 | 1.80 | .286 | 1.20 | 6.3 | 4.5 | 4.5 | 10.0 | 7 | 3 | 2 | 1 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 4.80 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 3 | 0 | 0 | 0 | 2.45 | .313 | 1.36 | 9.0 | 6.0 | 15.0 | 3.2 | 3 | 1 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.67 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 28 | 0 | 0 | 1 | 1.59 | .227 | 0.85 | 6.1 | 1.6 | 7.1 | 34.0 | 23 | 6 | 6 | 2 | 6 | 27 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 2.79 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 13 | 0 | 0 | 0 | 2.45 | .304 | 1.31 | 5.0 | 7.0 | 9.0 | 18.1 | 10 | 5 | 5 | 2 | 14 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.78 |