| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 24 | 24 | 11 | 7 | 2.84 | .286 | 1.19 | 7.3 | 3.4 | 8.4 | 161.2 | 131 | 60 | 51 | 13 | 61 | 151 | 2 | 0 | 0 | 2 | 16 | 2 | 1 | 3.35 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 23 | 23 | 4 | 8 | 5.85 | .345 | 1.58 | 10.9 | 3.3 | 4.5 | 103.0 | 125 | 73 | 67 | 20 | 38 | 52 | 0 | 0 | 0 | 0 | 5 | 0 | 5 | 5.62 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 22 | 22 | 7 | 9 | 5.47 | .347 | 1.58 | 10.8 | 3.5 | 3.7 | 130.0 | 156 | 89 | 79 | 16 | 50 | 54 | 5 | 0 | 0 | 0 | 8 | 1 | 1 | 4.95 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 46 | 0 | 3 | 5 | 2.98 | .262 | 1.04 | 6.0 | 3.4 | 9.4 | 42.1 | 28 | 16 | 14 | 9 | 16 | 44 | 0 | 31 | 4 | 0 | 0 | 1 | 2 | 4.90 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 30 | 0 | 2 | 2 | 3.56 | .321 | 1.42 | 8.1 | 4.8 | 9.6 | 30.1 | 27 | 15 | 12 | 3 | 16 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.77 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 74 | 25 | 0 | 2 | 1 | 2.73 | .295 | 1.25 | 5.9 | 5.5 | 13.5 | 26.1 | 17 | 9 | 8 | 3 | 16 | 39 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.35 |