| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 24 | 24 | 11 | 7 | 3.14 | .253 | 1.00 | 7.1 | 2.0 | 7.9 | 183.2 | 144 | 68 | 64 | 18 | 40 | 161 | 9 | 0 | 0 | 1 | 16 | 3 | 4 | 3.22 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 23 | 23 | 4 | 10 | 6.30 | .346 | 1.56 | 10.4 | 3.7 | 5.9 | 140.0 | 162 | 99 | 98 | 26 | 57 | 91 | 2 | 0 | 0 | 1 | 6 | 3 | 3 | 5.40 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 23 | 23 | 7 | 7 | 5.66 | .338 | 1.51 | 10.0 | 3.6 | 4.3 | 148.0 | 165 | 94 | 93 | 21 | 59 | 70 | 2 | 0 | 0 | 0 | 8 | 3 | 2 | 5.16 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 19 | 18 | 7 | 7 | 4.73 | .323 | 1.42 | 7.9 | 4.8 | 4.0 | 118.0 | 104 | 68 | 62 | 10 | 63 | 53 | 1 | 0 | 0 | 0 | 9 | 2 | 2 | 4.86 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 49 | 0 | 2 | 7 | 3.56 | .311 | 1.29 | 6.6 | 5.1 | 8.8 | 48.0 | 35 | 19 | 19 | 2 | 27 | 47 | 0 | 27 | 4 | 0 | 0 | 3 | 1 | 3.46 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 56 | 0 | 3 | 2 | 3.88 | .230 | 0.88 | 6.9 | 1.1 | 9.3 | 55.2 | 42 | 24 | 24 | 7 | 7 | 57 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.02 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 42 | 0 | 4 | 0 | 2.09 | .237 | 0.93 | 6.9 | 1.7 | 7.3 | 38.2 | 29 | 9 | 9 | 6 | 7 | 31 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.97 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 33 | 0 | 3 | 2 | 4.66 | .356 | 1.59 | 9.6 | 4.7 | 6.8 | 29.0 | 31 | 17 | 15 | 3 | 15 | 22 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 4.59 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 27 | 0 | 3 | 2 | 3.57 | .376 | 1.76 | 11.0 | 5.3 | 4.1 | 22.2 | 27 | 9 | 9 | 0 | 13 | 10 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 4.00 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 48 | 0 | 4 | 1 | 3.23 | .278 | 1.10 | 8.1 | 1.8 | 8.8 | 39.0 | 35 | 15 | 14 | 5 | 8 | 38 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.49 |