| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 13 | 14 | 3.90 | .283 | 1.18 | 8.3 | 2.3 | 9.3 | 203.1 | 188 | 94 | 88 | 32 | 51 | 210 | 1 | 0 | 0 | 1 | 20 | 2 | 0 | 3.76 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 33 | 33 | 15 | 7 | 3.68 | .292 | 1.23 | 8.2 | 2.9 | 4.7 | 230.0 | 210 | 111 | 94 | 17 | 73 | 121 | 6 | 0 | 0 | 2 | 20 | 1 | 4 | 3.87 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 33 | 32 | 4 | 16 | 6.48 | .339 | 1.51 | 10.8 | 2.9 | 8.0 | 166.2 | 199 | 130 | 120 | 37 | 53 | 148 | 1 | 0 | 0 | 0 | 11 | 5 | 3 | 5.16 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 33 | 31 | 12 | 12 | 6.08 | .358 | 1.65 | 11.1 | 3.9 | 4.7 | 180.2 | 222 | 128 | 122 | 23 | 77 | 93 | 5 | 0 | 1 | 1 | 8 | 3 | 3 | 4.96 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 79 | 0 | 5 | 10 | 4.50 | .288 | 1.20 | 8.1 | 2.7 | 8.1 | 84.0 | 76 | 43 | 42 | 9 | 25 | 76 | 0 | 29 | 8 | 0 | 0 | 1 | 2 | 3.51 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 89 | 0 | 8 | 1 | 2.90 | .271 | 1.10 | 5.8 | 4.1 | 7.2 | 99.1 | 64 | 36 | 32 | 6 | 45 | 79 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 3.62 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 75 | 0 | 5 | 3 | 6.06 | .363 | 1.71 | 10.7 | 4.8 | 10.7 | 84.2 | 100 | 61 | 57 | 20 | 45 | 100 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 5.32 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 63 | 0 | 3 | 3 | 4.83 | .341 | 1.51 | 10.8 | 3.0 | 8.1 | 72.2 | 86 | 42 | 39 | 10 | 24 | 65 | 0 | 2 | 1 | 0 | 0 | 3 | 9 | 4.13 |