| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 23 | 23 | 10 | 5 | 3.57 | .307 | 1.30 | 8.7 | 3.0 | 7.2 | 171.1 | 166 | 69 | 68 | 16 | 57 | 137 | 3 | 0 | 0 | 2 | 13 | 5 | 1 | 3.70 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 70 | 23 | 23 | 6 | 13 | 5.15 | .308 | 1.32 | 9.3 | 2.7 | 7.4 | 155.2 | 160 | 92 | 89 | 22 | 46 | 128 | 7 | 0 | 0 | 0 | 9 | 2 | 3 | 4.12 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 22 | 22 | 6 | 11 | 4.32 | .309 | 1.31 | 8.6 | 3.2 | 5.1 | 162.1 | 155 | 79 | 78 | 17 | 58 | 91 | 4 | 0 | 0 | 2 | 11 | 5 | 4 | 4.41 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 23 | 22 | 4 | 11 | 5.61 | .348 | 1.58 | 10.4 | 3.8 | 4.6 | 138.0 | 159 | 91 | 86 | 23 | 59 | 71 | 2 | 0 | 0 | 1 | 7 | 3 | 5 | 5.49 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 58 | 0 | 8 | 1 | 3.74 | .294 | 1.25 | 7.4 | 3.9 | 8.5 | 79.1 | 65 | 33 | 33 | 4 | 34 | 75 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 3.05 |
| RP | Nathan, J.Nathan, Joe # >> | 32 | 2006 | R | 87 | 46 | 0 | 1 | 5 | 4.69 | .333 | 1.50 | 8.4 | 5.1 | 8.1 | 48.0 | 45 | 27 | 25 | 5 | 27 | 43 | 0 | 5 | 3 | 0 | 0 | 0 | 2 | 4.25 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 35 | 0 | 0 | 4 | 3.05 | .326 | 1.40 | 8.8 | 4.0 | 9.0 | 41.1 | 40 | 16 | 14 | 4 | 18 | 41 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.73 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 22 | 0 | 1 | 3 | 5.25 | .327 | 1.46 | 8.6 | 4.5 | 8.6 | 24.0 | 23 | 14 | 14 | 2 | 12 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.67 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 23 | 0 | 0 | 1 | 5.33 | .361 | 1.66 | 10.8 | 4.3 | 8.6 | 25.1 | 30 | 15 | 15 | 4 | 12 | 24 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.72 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 20 | 0 | 0 | 3 | 7.06 | .369 | 1.75 | 12.9 | 3.4 | 6.4 | 21.2 | 30 | 17 | 17 | 4 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.19 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 8 | 1 | 0 | 2 | 8.76 | .373 | 1.78 | 11.3 | 5.3 | 6.0 | 12.1 | 15 | 12 | 12 | 4 | 7 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.75 |