| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 30 | 30 | 6 | 6 | 3.26 | .287 | 1.18 | 8.3 | 2.5 | 8.7 | 132.2 | 121 | 50 | 48 | 17 | 36 | 128 | 0 | 0 | 0 | 0 | 2 | 3 | 6 | 3.62 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 30 | 30 | 2 | 6 | 3.47 | .315 | 1.37 | 8.9 | 3.4 | 5.8 | 122.0 | 121 | 53 | 47 | 14 | 46 | 79 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4.35 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 29 | 29 | 13 | 9 | 4.60 | .304 | 1.28 | 8.9 | 2.7 | 6.1 | 189.2 | 186 | 100 | 97 | 27 | 57 | 128 | 0 | 0 | 0 | 0 | 15 | 5 | 4 | 4.49 |
| SP | Webb, B.Webb, Brandon # >> | 24 | 2003 | R | 64 | 29 | 29 | 10 | 10 | 6.04 | .355 | 1.61 | 9.9 | 4.6 | 7.7 | 174.1 | 191 | 125 | 117 | 37 | 89 | 149 | 0 | 0 | 0 | 0 | 8 | 8 | 7 | 5.72 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 29 | 29 | 6 | 11 | 5.23 | .340 | 1.51 | 9.7 | 3.9 | 6.5 | 172.0 | 186 | 110 | 100 | 28 | 74 | 124 | 0 | 0 | 0 | 0 | 12 | 6 | 5 | 5.07 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 79 | 0 | 9 | 5 | 4.02 | .289 | 1.20 | 8.3 | 2.6 | 9.7 | 109.2 | 101 | 50 | 49 | 15 | 31 | 117 | 0 | 7 | 5 | 0 | 0 | 2 | 3 | 3.55 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 66 | 75 | 0 | 6 | 4 | 3.96 | .297 | 1.24 | 8.8 | 2.4 | 8.6 | 97.2 | 95 | 43 | 43 | 14 | 26 | 93 | 0 | 8 | 3 | 0 | 0 | 3 | 0 | 3.86 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 50 | 66 | 0 | 3 | 3 | 4.60 | .338 | 1.50 | 9.8 | 3.7 | 6.3 | 86.0 | 94 | 44 | 44 | 10 | 35 | 60 | 0 | 12 | 4 | 0 | 0 | 3 | 2 | 4.44 |
| RP | Guerrier, M.Guerrier, Matt >> | 31 | 2009 | R | 40 | 59 | 0 | 4 | 3 | 4.08 | .308 | 1.31 | 9.2 | 2.5 | 6.0 | 75.0 | 77 | 34 | 34 | 14 | 21 | 50 | 0 | 6 | 3 | 0 | 0 | 2 | 7 | 5.01 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 50 | 4 | 0 | 0 | 1 | 1.50 | .250 | 1.00 | 4.5 | 4.5 | 10.5 | 6.0 | 3 | 4 | 1 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.50 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 33 | 0 | 6 | 6 | 4.60 | .336 | 1.45 | 7.1 | 6.1 | 10.3 | 62.2 | 49 | 32 | 32 | 12 | 42 | 71 | 0 | 4 | 3 | 0 | 0 | 4 | 0 | 5.45 |