| SP | Schmidt, J.Schmidt, Jason † >> | 30 | 2003 | R | 99 | 31 | 31 | 13 | 13 | 3.95 | .284 | 1.17 | 7.9 | 2.6 | 9.6 | 198.0 | 173 | 88 | 87 | 26 | 58 | 212 | 4 | 0 | 0 | 1 | 17 | 5 | 6 | 3.52 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 80 | 30 | 30 | 8 | 11 | 7.27 | .367 | 1.69 | 12.5 | 2.8 | 6.4 | 138.2 | 191 | 118 | 112 | 33 | 43 | 98 | 2 | 0 | 0 | 0 | 7 | 7 | 3 | 5.78 |
| SP | Perez, O.Perez, Oliver $$ >> | 23 | 2004 | L | 75 | 29 | 29 | 9 | 8 | 5.34 | .343 | 1.56 | 8.9 | 5.1 | 8.8 | 150.0 | 149 | 90 | 89 | 31 | 85 | 147 | 0 | 0 | 0 | 0 | 7 | 1 | 3 | 5.45 |
| SP | Bedard, E.Bedard, Erik # >> | 28 | 2007 | L | 79 | 29 | 29 | 8 | 10 | 5.52 | .327 | 1.44 | 9.3 | 3.6 | 9.9 | 148.1 | 153 | 94 | 91 | 32 | 60 | 162 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 4.90 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 77 | 28 | 28 | 13 | 6 | 4.17 | .310 | 1.33 | 10.1 | 1.8 | 5.4 | 166.0 | 186 | 80 | 77 | 24 | 34 | 99 | 1 | 0 | 0 | 1 | 16 | 4 | 2 | 4.37 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 79 | 0 | 3 | 2 | 4.55 | .326 | 1.43 | 9.2 | 3.6 | 9.7 | 87.0 | 89 | 46 | 44 | 11 | 35 | 94 | 0 | 0 | 2 | 0 | 0 | 2 | 3 | 3.76 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 89 | 74 | 0 | 5 | 2 | 4.85 | .315 | 1.38 | 7.9 | 4.6 | 5.4 | 72.1 | 63 | 39 | 39 | 11 | 37 | 43 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 5.33 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 80 | 0 | 6 | 2 | 3.28 | .306 | 1.25 | 8.6 | 2.8 | 9.4 | 68.2 | 65 | 26 | 25 | 9 | 21 | 71 | 0 | 0 | 0 | 0 | 0 | 5 | 2 | 3.78 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 67 | 0 | 4 | 1 | 3.42 | .278 | 1.08 | 6.9 | 2.9 | 5.7 | 68.1 | 52 | 26 | 26 | 6 | 22 | 43 | 0 | 2 | 0 | 0 | 0 | 5 | 3 | 4.07 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 58 | 44 | 0 | 1 | 1 | 2.72 | .268 | 1.08 | 6.5 | 3.3 | 7.8 | 46.1 | 33 | 14 | 14 | 3 | 17 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.28 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 67 | 6 | 0 | 1 | 1 | 3.38 | .400 | 2.00 | 13.5 | 4.5 | 3.4 | 8.0 | 12 | 3 | 3 | 0 | 4 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.75 |
| CL | Wagner, B.Wagner, Billy $ >> | 33 | 2004 | L | 91 | 57 | 0 | 0 | 8 | 4.40 | .288 | 1.21 | 8.7 | 2.3 | 9.0 | 59.1 | 57 | 31 | 29 | 6 | 15 | 59 | 0 | 34 | 3 | 0 | 0 | 0 | 3 | 3.08 |
| SU | Betancourt, R.Betancourt, Rafael $ >> | 32 | 2007 | R | 87 | 53 | 0 | 3 | 3 | 5.02 | .304 | 1.27 | 8.7 | 2.8 | 8.8 | 57.1 | 55 | 34 | 32 | 14 | 18 | 56 | 0 | 2 | 6 | 0 | 0 | 2 | 0 | 5.28 |